Ethics code: IR.UMSHA.REC.1401.541
Abstract: (5 Views)
A B S T R A C T
Background and Objectives
Clinical decision-making regarding red blood cell (RBC) transfusion is based on a comprehensive assessment of patient’s clinical condition. The transfusion index (number of transfused RBC units per patients for whom cross-matching was performed) and the crossmatch-to-transfusion (C/T) ratio are key indicators for evaluating blood utilization and system performance. Assessing these indices becomes particularly critical during outbreaks of emerging infectious diseases and other public health crises. This study aimed to determine the Transfusion Index, C/T ratio and to examin association of age and sex with blood request and transfusion among hospitalized patients at Besat hospital, Hamadan, in COVID-19 pandemic during 2021.
Materials and Methods
This retrospective cross-sectional study was conducted on 560 patients admitted to Besat Hospital, Hamadan during 2021, coinciding with the COVID-19 pandemic. Data were extracted from patient medical record an included age, sex, reason for hospitalization, hemoglobin level at the time of blood request, number of requested RBC units, and number of RBC units actually transfused. The transfusion index and C/T ratio were calculated based on collected data. Data were analyzed using SPSS software version 24, employing independent t-test and Pearson correlation coefficient. A significance level of <0.05 was considered statitically significant.
Results
The mean hemoglobin level at the time of blood request was 9.46 g/dL. A total of 1,527 RBC units were requested and cross matched, of which 1,024 units were ultimately transfused. The C/T ratio was 1.49, and the transfusion index was 1.83. A significant direct correlation was observed between patient age and both the number of requested RBC units (r = 0.301, p = 0.003) and the number of transfused units (r = 0.226, p = 0.036). No significant differences were found between the sex and the number of requested or transfused RBC units.
Conclusions
The transfusion index and C/T ratio during COVID-19 pandemic were within acceptable ranges and did not differ from those reported under non-pandemic conditions. Older patients were found to requires significantly more RBC units in terms of both requests and transfusions. These finding suggest that adherence to transfusion guidelines, enables appropriate management of blood component utilization and minimize the risk of transfusion-related adverse events, even during widespread infectious disease outbreaks.
Background and Objectives
Clinical decision-making regarding red blood cell (RBC) transfusion is based on a comprehensive assessment of patient’s clinical condition. The transfusion index (number of transfused RBC units per patients for whom cross-matching was performed) and the crossmatch-to-transfusion (C/T) ratio are key indicators for evaluating blood utilization and system performance. Assessing these indices becomes particularly critical during outbreaks of emerging infectious diseases and other public health crises. This study aimed to determine the Transfusion Index, C/T ratio and to examin association of age and sex with blood request and transfusion among hospitalized patients at Besat hospital, Hamadan, in COVID-19 pandemic during 2021.
Materials and Methods
This retrospective cross-sectional study was conducted on 560 patients admitted to Besat Hospital, Hamadan during 2021, coinciding with the COVID-19 pandemic. Data were extracted from patient medical record an included age, sex, reason for hospitalization, hemoglobin level at the time of blood request, number of requested RBC units, and number of RBC units actually transfused. The transfusion index and C/T ratio were calculated based on collected data. Data were analyzed using SPSS software version 24, employing independent t-test and Pearson correlation coefficient. A significance level of <0.05 was considered statitically significant.
Results
The mean hemoglobin level at the time of blood request was 9.46 g/dL. A total of 1,527 RBC units were requested and cross matched, of which 1,024 units were ultimately transfused. The C/T ratio was 1.49, and the transfusion index was 1.83. A significant direct correlation was observed between patient age and both the number of requested RBC units (r = 0.301, p = 0.003) and the number of transfused units (r = 0.226, p = 0.036). No significant differences were found between the sex and the number of requested or transfused RBC units.
Conclusions
The transfusion index and C/T ratio during COVID-19 pandemic were within acceptable ranges and did not differ from those reported under non-pandemic conditions. Older patients were found to requires significantly more RBC units in terms of both requests and transfusions. These finding suggest that adherence to transfusion guidelines, enables appropriate management of blood component utilization and minimize the risk of transfusion-related adverse events, even during widespread infectious disease outbreaks.
Type of Study: Research |
Subject:
Imunohematology
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