Scientific Journal of

  Abstract

 Background and Objectives

  Bombay phenotype donors do not have H Antigen on the surface of their red blood cells and have hemolytic anti-H in their sera so, this group should receive autologous blood and donation of their blood as O blood group can lead to severe hemolysis in recipients. Therefore, it is important to detect them.

  Case

  A 46-year-old man living in Bushehr for many years has been recognized as O⁺ blood group. Preliminary diagnosis was made by the use of antibody screening agglutination test. In serologic studies, we detected high level of anti-H, anti-A, and anti-B. Direct coombs was also negative. Definite diagnosis was made with no red cell agglutination in the presence of anti-H. Complementary serologic studies showed that Kelly antigen was negative and Rh genotype was CD/cde.

 Conclusions

  This case increased the number of Bombay phenotypes in the world to 131 and in Iran to 11. It seems that this latter number is higher than official estimations of its prevalence (10^-6). Therefore, the use of antibody screening test should be considered in screening blood donations.

 Key words: Bombay, phenotype, Blood donors, H blood group system, anti-H, Autologous transfusion