Volume 13, Issue 1 (Spring 2016)                   Sci J Iran Blood Transfus Organ 2016, 13(1): 72-82 | Back to browse issues page

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Poormansouri S, Ahmadi M, Shariati A, Keikhaei B. Quality of life, depression, anxiety and stress in over-18-year-old patients with beta-Thalassemia major. Sci J Iran Blood Transfus Organ 2016; 13 (1) :72-82
URL: http://bloodjournal.ir/article-1-957-en.html
Quality of life, depression, anxiety and stress in over-18-year-old patients with beta-Thalassemia major
S. Poormansouri , M. Ahmadi * , A.A. Shariati , B. Keikhaei
Keywords: Key words: Quality of Life, Depression, Anxiety, beta Thalassemia
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Sci J Iran Blood Transfus Organ 2016; 13(1): 72-82
 
Original  Article
 
 

Quality of life, depression, anxiety and stress in
over-18-year-old patients with beta-Thalassemia major
 
Poormansouri S.1, Ahmadi M.2, Shariati A.A.2, Keikhaei B.3
 
1Nursing and Midwifery School, Kashan University of Medical Sciences, Kashan, Iran.
2Nursing and Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3Health Research Institute, Research Center of Thalassemia and Hemoglobinopathy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
 
Abstract
Background and Objectives
Patients with beta-Thalassemia major (β-TM) in dealing with the serious complications of the disease experience many physical and psychological problems that affect their quality of life (QOL). The aim of this study was to determine QOL, depression, anxiety and stress in β-TM patients over 18 years of age.
 
Materials and Methods
The participants of this cross-sectional study were 142 β-TM patients (77 female, 65 male) having referred to the Thalassemia Clinic of Shafa Hospital in 2014; they were entered into the study by the census method. Data collection instrument consisted of three parts including demographic questions, the SF-36 questionnaire and the DAS-21 scale. The data were analyzed using descriptive statistics, independent sample t- test, one way ANOVA and correlation in SPSS software v.19.
 
Results
The participants obtained a mean score of 63.53 ± 18.12 for QOL, 6.64 ± 5.07 for depression, 5.03 ± 3.95 for anxiety and 7.68 ± 4.98 for stress. The significant inverse correlations were found between QOL and that of depression (p < 0.001, r = -0.58), anxiety (p < 0.001, r = -0.52), and stress scores (p < 0.001, r = -0.45). The mean scores of QOL were higher in the patients with college degrees, being employed, being married, under regular chelation therapy without presence of comorbidities. The mean scores of depression, anxiety, and stress were higher in patients with education ≤ high school diploma, being poorly complied with iron-chelating therapy in presence of comorbidities.
 
Conclusions
The study showed that β-TM patients experienced a considerable decrease in their QoL. A majority of the patients also suffered from mild to severe depression, anxiety and stress. Obviously, the health improvement, and social and economic as well as psychological support may raise their QOL.
 
             Key words: Quality of Life, Depression, Anxiety, beta Thalassemia
 
 
 
Received: 24 May 2015
Accepted: 23 Nov 2015
 
 
 
 

Correspondence: Ahmadi M., MSc of Nursing. Nursing and Midwifery School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
P.O.Box: 61357-15794, Ahvaz, Iran. Tel: (+9861) 33910499; Fax: (+9861) 33337690
E-mail: mer.ahmadi@gmail.com
Type of Study: Research | Subject: General
Published: 2016/03/15
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