[Home ] [Archive]   [ فارسی ]  
:: Main :: About us :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 13, Issue 1 (Spring 2016) ::
Sci J Iran Blood Transfus Organ 2016, 13(1): 72-82 Back to browse issues page
Quality of life, depression, anxiety and stress in over-18-year-old patients with beta-Thalassemia major
S. Poormansouri, M. Ahmadi , A.A. Shariati, B. Keikhaei Dr.
Abstract:   (5759 Views)


Background and Objectives

Patients with beta-Thalassemia major (β-TM) in dealing with the serious complications of the disease experience many physical and psychological problems that affect their quality of life (QOL). The aim of this study was to determine QOL, depression, anxiety and stress in β-TM patients over 18 years of age.

Materials and Methods

The participants of this cross-sectional study were 142 β-TM patients (77 female, 65 male) having referred to the Thalassemia Clinic of Shafa Hospital in 2014; they were entered into the study by the census method. Data collection instrument consisted of three parts including demographic questions, the SF-36 questionnaire and the DAS-21 scale. The data were analyzed using descriptive statistics, independent sample t- test, one way ANOVA and correlation in SPSS software v.19.


The participants obtained a mean score of 63.53 ± 18.12 for QOL, 6.64 ± 5.07 for depression, 5.03 ± 3.95 for anxiety and 7.68 ± 4.98 for stress. The significant inverse correlations were found between QOL and that of depression (p < 0.001, r = -0.58), anxiety (p < 0.001, r = -0.52), and stress scores (p < 0.001, r = -0.45). The mean scores of QOL were higher in the patients with college degrees, being employed, being married, under regular chelation therapy without presence of comorbidities. The mean scores of depression, anxiety, and stress were higher in patients with education &le; high school diploma, being poorly complied with iron-chelating therapy in presence of comorbidities.


The study showed that &beta;-TM patients experienced a considerable decrease in their QoL. A majority of the patients also suffered from mild to severe depression, anxiety and stress. Obviously, the health improvement, and social and economic as well as psychological support may raise their QOL.


Keywords: Key words: Quality of Life, Depression, Anxiety, beta Thalassemia
Full-Text [PDF 313 kb]   (1439 Downloads) |   |   Full-Text (HTML)  (1785 Views)  
Type of Study: Research | Subject: General
Published: 2016/03/15
Send email to the article author

Add your comments about this article
Your username or Email:


XML   Persian Abstract   Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Poormansouri S, Ahmadi M, Shariati A, Keikhaei B. Quality of life, depression, anxiety and stress in over-18-year-old patients with beta-Thalassemia major. Sci J Iran Blood Transfus Organ. 2016; 13 (1) :72-82
URL: http://bloodjournal.ir/article-1-957-en.html

Volume 13, Issue 1 (Spring 2016) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 4319