Volume 21, Issue 3 (Autumn 2024)                   Sci J Iran Blood Transfus Organ 2024, 21(3): 236-244 | Back to browse issues page

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Vafaee H, Pourmotabed S, Amiri F. Impact of blood cell count on disease severity in Covid-19 inpatients in an educational hospital of Hamadan. Sci J Iran Blood Transfus Organ 2024; 21 (3) :236-244
URL: http://bloodjournal.ir/article-1-1551-en.html
Impact of blood cell count on disease severity in Covid-19 inpatients in an educational hospital of Hamadan
H. Vafaee , S. Pourmotabed , F. Amiri *
Keywords: Key words: Covid-19, Red Blood Cells, White Blood Cells, Platelets
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Sci J Iran Blood Transfus Organ 2024; 21 (3): 236-244
Original Article
 
Impact of blood cell count on disease severity in Covid-19 inpatients in an educational hospital
of Hamadan

Vafaee H.1, Pourmotabed S.2, Amiri F.3


1School of Medicine, Hamadan University of Medical Science, Hamadan, Iran
2School of Medicine, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran
3School of Paramedicine, Hamadan University of Medical Sciences, Hamadan, Iran

Abstract
Background and Objectives
Count of blood cells alters in the Covid-19 patients and by identifying its relationship with disease severity, the proper treatment could be provided. The present study was conducted with the aim of investigating the relationship between blood cell count and the disease severity of Covid-19.

Materials and Methods
This retrospective cross-sectional study was conducted on profiles of 370 inpatients with Covid-19 in a hospital in Hamadan. The disease severity in inpatients was classified as acute/ high risk and as severe types using by world health organization guideline and author previous studies. Blood cell counts were obtained from patient profiles and cell counter. The collected data were analyzed using SPSS version 24 software. Chi square, independent T-test and logistic regression were used for data analysis with significance level of p< 0.05.

Results
The mean count of red blood cell, white blood cell and platelet in patients with acute and high-risk form of Covid-19 were lower (p= 0.001), higher (p= 0.005) and lower (p= 0.001), respectively in comparison to severe form. According to logistic regression results, red blood cell, white blood cell and platelet count had impact on disease severity meaningfully (p = 0.003, 0.004, and 0.003 respectively).

Conclusions 
Red blood cell count is one of the influential factors on disease severity of Covid-19. Therefore, these parameters could be used as determining indicators in the assessment of disease severity and better treatment management in the Covid-19 patients.

Key words: Covid-19, Red Blood Cells, White Blood Cells, Platelets







Received:  21 Aug 2024
Accepted: 14 Sep  2024



Correspondence: Amiri F., PhD of Hematology & Blood Banking. Assistant Professor in Department of Medical Laboratory Sciences, School of Paramedicine, Hamadan University of Medical Sciences.
Postal Code: 6517838741, Hamadan, Iran. Tel: (+9881) 38380109; Fax: (+9881) 38381017
E-mail: f.amiri@umsha.ac.ir
 
Type of Study: Research | Subject: Hematology
Published: 2024/10/1
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