Abstract Background and Objectives Count of blood cells alters in the Covid-19 patients and by identifying its relationship with disease severity, the proper treatment could be provided. The present study was conducted with the aim of investigating the relationship between blood cell count and the disease severity of Covid-19.
Materials and Methods This retrospective cross-sectional study was conducted on profiles of 370 inpatients with Covid-19 in a hospital in Hamadan. The disease severity in inpatients was classified as acute/ high risk and as severe types using by world health organization guideline and author previous studies. Blood cell counts were obtained from patient profiles and cell counter. The collected data were analyzed using SPSS version 24 software. Chi square, independent T-test and logistic regression were used for data analysis with significance level of p< 0.05.
Results The mean count of red blood cell, white blood cell and platelet in patients with acute and high-risk form of Covid-19 were lower (p= 0.001), higher (p= 0.005) and lower (p= 0.001), respectively in comparison to severe form. According to logistic regression results, red blood cell, white blood cell and platelet count had impact on disease severity meaningfully (p = 0.003, 0.004, and 0.003 respectively).
Conclusions Red blood cell count is one of the influential factors on disease severity of Covid-19. Therefore, these parameters could be used as determining indicators in the assessment of disease severity and better treatment management in the Covid-19 patients.
Vafaee H, Pourmotabed S, Amiri F. Impact of blood cell count on disease severity in Covid-19 inpatients in an educational hospital of Hamadan. Sci J Iran Blood Transfus Organ 2024; 21 (3) :236-244 URL: http://bloodjournal.ir/article-1-1551-en.html