Volume 14, Issue 2 (Summer 2017)
Sci J Iran Blood Transfus Organ 2017, 14(2): 135-139 |
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Gholipour S, Gholipour S, Zargham A. Correlation of congenital abnormalities with blood groups in children admitted to the pediatric surgery ward of Isfahan Alzahra Hospital in 2008-2014. Sci J Iran Blood Transfus Organ 2017; 14 (2) :135-139
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Correlation of congenital abnormalities with blood groups in children admitted to the pediatric surgery ward of Isfahan Alzahra Hospital in 2008-2014
Gholipour Sh.1, Gholipour Sh.2, Zargham A.3
1Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
2School of Science, Isfahan University, Isfahan, Iran
3Nursing and Midwifery Faculty, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background and Objectives
The correlation between ABO blood group distribution and congenital abnormalities has not been evaluated in the past studies. This study investigated the correlation between the frequency of congenital abnormalities and ABO/Rh blood groups in a sample population over a period of 6 years.
Materials and Methods
In this descriptive and retrospective study, the ABO and Rh blood groups of 455 admitted children were determined in Alzahra Hospital, Isfahan, Iran, from 2008 to 2014. Demographic data were collected in the medical record unit. We analyzed the demographic data and ABO/Rh frequencies based on the patients file information by SPSS 16, c2 and t-Test.
Results
In this study, we observed an overall trend of anomaly in both male and female newborns: with the urinary tract anomalies in 341 male newborns (74.9%) and the head and neck defects in 114 female newborns (25.1%). The anomalies in the gastrointestinal and urinary systems of Rh-negative children and the facial anomalies in Rh-positive children were more significantly frequent compared to others.
Conclusions
There was a significant positive correlation between the Rh distribution and congenital abnormalities; however, no significant correlation was observed between ABO blood groups and anomalies in different organs.
Key words: ABO Blood group system, RH Blood group, congenital abnormalities
Received: 20 Jul 2016
Accepted: 27 Feb 2017
Correspondence: Gholipour Sh., BS in Nursing. Alzahra Hospital, Isfahan University of Medical Sciences, Hezarjarib St.
Postal Code: 8174673461, Isfahan, Iran. Tel: (+9831) 36201250; Fax: (+9831) 36201250
E-mail:
Sh.gholipour69@gmail.com
Full-Text: (4841 Views)
References:
- Jörgensen G. The ABO blood group-polymorphism in the multifactorial genetic system. Humangenetik. 1967; 3(3): 264-8.
- D'Adamo P. Birth Defects and ABO Blood Groups. THE INDIVIDUALIST A knowledgebase of biochemical individuality; 2006. Available from: http://www.drpeterjdadamo.com/wiki/wiki.pl/Birth_Defects_and_ABO_Blood_Groups.
- Czeizel AE. Birth defects are preventable. Int J Med Sc 2005; 2(3): 91-2.
- Stevenson RE. The Genetic Basis of Human Anomalies. In: Stevenson RE, Hall JG, Everman DB, Solomon BD. Human Malformations and Related Anomalies. 3rd ed. New York: Oxford University Press; 1993. p. 115.
- Buckwalter JA. Disease associations of the ABO blood
group. Acta Genet Stat Med 1956-1957; 6(4): 561-3. - Ghalenoei B, Fani A, Monzavi-poor S, Shokri Noor Eini M. Investigating the relation between ABO blood group and Rh with peptic ulcer. Journal of Arak University of Medical Sciences 2007; 10(4): 1-5. [Article in Farsi]
- Stamatakos M, Kontzoglou K, Safioleas P, Safioleas C, Manti C, Safioleas M. Breast cancer incidence in Greek women in relation to ABO blood groups and Rh factor. Int Semin Surg Oncol 2009; 6: 14.
- Xie J, Qureshi AA, Li Y, Han J. ABO blood group and incidence of skin cancer. PLoS One 2010; 5(8): e11972.
- Aflatoonian M, Zohoor A. The relationship between blood groups/RH factor and Cholera disease (in Persian). Payesh 2002; 1(4): 12-8. [Article in Farsi]
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Sci J Iran Blood Transfus Organ 2017; 14(2): 135-139 |
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Short Communication
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Correlation of congenital abnormalities with blood groups in children admitted to the pediatric surgery ward of Isfahan Alzahra Hospital in 2008-2014
Gholipour Sh.1, Gholipour Sh.2, Zargham A.3
1Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
2School of Science, Isfahan University, Isfahan, Iran
3Nursing and Midwifery Faculty, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Background and Objectives
The correlation between ABO blood group distribution and congenital abnormalities has not been evaluated in the past studies. This study investigated the correlation between the frequency of congenital abnormalities and ABO/Rh blood groups in a sample population over a period of 6 years.
Materials and Methods
In this descriptive and retrospective study, the ABO and Rh blood groups of 455 admitted children were determined in Alzahra Hospital, Isfahan, Iran, from 2008 to 2014. Demographic data were collected in the medical record unit. We analyzed the demographic data and ABO/Rh frequencies based on the patients file information by SPSS 16, c2 and t-Test.
Results
In this study, we observed an overall trend of anomaly in both male and female newborns: with the urinary tract anomalies in 341 male newborns (74.9%) and the head and neck defects in 114 female newborns (25.1%). The anomalies in the gastrointestinal and urinary systems of Rh-negative children and the facial anomalies in Rh-positive children were more significantly frequent compared to others.
Conclusions
There was a significant positive correlation between the Rh distribution and congenital abnormalities; however, no significant correlation was observed between ABO blood groups and anomalies in different organs.
Key words: ABO Blood group system, RH Blood group, congenital abnormalities
Received: 20 Jul 2016
Accepted: 27 Feb 2017
Correspondence: Gholipour Sh., BS in Nursing. Alzahra Hospital, Isfahan University of Medical Sciences, Hezarjarib St.
Postal Code: 8174673461, Isfahan, Iran. Tel: (+9831) 36201250; Fax: (+9831) 36201250
E-mail:
Sh.gholipour69@gmail.com
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