Volume 14, Issue 2 (Summer 2017)                   Sci J Iran Blood Transfus Organ 2017, 14(2): 135-139 | Back to browse issues page

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Gholipour S, Gholipour S, Zargham A. Correlation of congenital abnormalities with blood groups in children admitted to the pediatric surgery ward of Isfahan Alzahra Hospital in 2008-2014. Sci J Iran Blood Transfus Organ 2017; 14 (2) :135-139
URL: http://bloodjournal.ir/article-1-1056-en.html
Abstract:   (4494 Views)

Abstract

Background and Objectives

The correlation between ABO blood group distribution and congenital abnormalities has not been evaluated in the past studies. This study investigated the correlation between the frequency of congenital abnormalities and ABO/Rh blood groups in a sample population over a period of 6 years.

Materials and Methods

In this descriptive and retrospective study, the ABO and Rh blood groups of 455 admitted children were determined in Alzahra Hospital, Isfahan, Iran, from 2008 to 2014. Demographic data were collected in the medical record unit. We analyzed the demographic data and ABO/Rh frequencies based on the patients file information by SPSS 16, c2 and t-Test.

Results

In this study, we observed an overall trend of anomaly in both male and female newborns: with the urinary tract anomalies in 341 male newborns (74.9%) and the head and neck defects in 114 female newborns (25.1%). The anomalies in the gastrointestinal and urinary systems of Rh-negative children and the facial anomalies in Rh-positive children were more significantly frequent compared to others.

Conclusions  

There was a significant positive correlation between the Rh distribution and congenital abnormalities; however, no significant correlation was observed between ABO blood groups and anomalies in different organs.

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Type of Study: Short Communication | Subject: Hematology
Published: 2017/06/19

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