[Home ] [Archive]   [ فارسی ]  
:: Main :: About us :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 2, Issue 5 (Autumn 2005) ::
Sci J Iran Blood Transfus Organ 2005, 2(5): 157-162 Back to browse issues page
Frequency of antibodies to hepatitis E virus among male blood donors in Tabriz
L. Gachkar, M. Taremi, M. Khoshbaten, S.M. Mahmoodarabi, M. Kheradpezhouh, R. Dehkhoda, S.E. Torabi
Abstract:   (21947 Views)

  Abstract

  

 Background and Objectives

  Hepatitis E virus (HEV) causes enterically transmitted acute viral hepatitis. Hepatitis E virus infection spreads by the fecal-oral route. However, blood donors might transmit HEV during the transient phase of viremia that precedes the onset of symptoms. To our knowledge, few reports on the prevalence of Hepatitis E in Iranian blood donors exist. The aim of this study was to evaluate the frequency of anti-HEV among male blood donors in Tabriz.

 

  Materials and Methods

  This cross-sectional study was carried out between July and August 2004 in Tabriz. Serum samples were collected from 399 voluntary male blood donors and tested for anti-HEV IgG using EIA. All the subjects were negative for anti-HIV, anti-HBV and anti-HCV antibodies.

  

 Results

  The prevalence of anti-HEV IgG among 399 blood donors was 7.8% (95% CI: 5.2%-10.4%). Seropositive subjects had a mean of 40.7 ± 12.4 SD. Donors who were 40 and older (14 out of 83) had significantly higher seroprevalence than those who were younger than 40 (17 of 316) (p<0.001). 3 of 11 illiterate donors had anti-HEV IgG. Among educated donors 10 of 88, 14 of 206 and 4 of 94 in elementary, intermediate and college levels were positive respectively (p<0.025).

 

 Conclusions

  These findings demonstrate the high seropositive rate of anti-HEV among male blood donors in Iran that is compatible with endemicity of this virus in our country.

  

  

 Key words: Blood donor, Hepatitis E, HEV

Keywords: Blood donor, Hepatitis E, HEV
Full-Text [PDF 193 kb]   (2827 Downloads)    
Type of Study: Research | Subject: General
Published: 2014/06/30
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Gachkar L, Taremi M, Khoshbaten M, Mahmoodarabi S, Kheradpezhouh M, Dehkhoda R et al . Frequency of antibodies to hepatitis E virus among male blood donors in Tabriz. Sci J Iran Blood Transfus Organ. 2005; 2 (5) :157-162
URL: http://bloodjournal.ir/article-1-40-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 2, Issue 5 (Autumn 2005) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
Persian site map - English site map - Created in 0.05 seconds with 31 queries by YEKTAWEB 4414