Abstract
Background and Objectives
Blood safety is one of the most important challenges at blood centers worldwide. The aim of this study was to investigate the trend of confidential unit-exclusion and the efficacy of the CUE procedure on the improvement of blood safety at Blood Cenetr of Kohgiluyeh and Buyerahmad province.
 
Materials and Methods
In the present descriptive study, the rate of CUE was compared among first-time, repeated and regular donors of Kohgilouyeh and Boyerahmad province from 2006 to 2014. Data were extracted from blood donor database. Then, blood donors were classified into two groups: CUE and non CUE. SPSS 16 & Chi-square statistical test was used for data analysis.
 
Results
In this retrospective study, the use of CUE practice in the studied years was on the upward trend. The minimum number of confidential unit-exclusion was related to first three years (310), and the highest number was related to the last three years (805) (p < 0.0001).
The frequency of hepatitis B and C was significantly higher in the CUE  group than non-CUE group (p < 0.0001).  None of the donors in this group were positive for HIV Ab.
 
Conclusions 
Although the use of CUE has led to the loss of a number of donors, it is effective in promoting blood safety in this province. Then, this practice can be used to improve blood safety in Iran because of its suitable status in the Middle East in the field of blood transfusion and effective cultural efforts made for the promotion of blood donation.