Journal of Iranian Blood Transfusion

Abstract

Background and Objectives

One method of autologous transfusion is acute normovolemic hemodilution (ANH) that involves withdrawal of whole blood shortly before surgery with infusion of fluids to maintain normovolemia.

Materials and Methods

A retrospective study was carried out during 2013-2014 at Tehran Blood Centre. The data regarded different cardiac surgery hospitals which performed acute normovolemic hemodilution in their operating room. We analyzed adverse events included arrhythmia (atrial fibrillation, premature ventricular contraction) and unstable hemodynamic from collecting blood to 30 minutes.

Results

308 patients scheduled for acute normovolemic hemodilution during cardiac surgery and were evaluated adverse events. We assessed 266 (86.4%) Cardiopulmonary bypass graft patient, 20 (6.6%) patients  mitral valve replacement and aorta valve replacement, two valves replacement concurrent in 3 (0.9%) patients (MVR+AVR) (MVR+  TVR), 10 mitral valve replacement with CABG and, congenital heart disease in 7 (2.3%) patients and 2 (0.6%) Bental repair. No significant hemodynamic changes and arrhythmia were recorded.

Conclusions

In this survey, No patients didn't show any adverse events (arrhythmia and unstable hemodynamic) during and 30 minutes after phlebotomy. Acute normovolemic hemodilution safely could perform in cardiac surgery patients with CABG, valvular replacement.