Volume 13, Issue 2 (Summer 2016)                   bloodj 2016, 13(2): 156-162 | Back to browse issues page

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Ghezelbash B, Moghaddam M, Naghi A. A case report of a patient with alloantibodies and multiple abortions . bloodj 2016; 13 (2) :156-162
URL: http://bloodjournal.ir/article-1-961-en.html
A case report of a patient with alloantibodies and multiple abortions
B. Ghezelbash * , M. Moghaddam , A. Naghi
Keywords: Key words: Alloantibodies, Previous Abortion, screening
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Case Report
 
 
 
 
Sci J Iran Blood Transfus Organ 2016; 13(2): 156-162
 
 
 

A case report of a patient with alloantibodies
and multiple abortions
 
Ghezelbash B.1,2, Moghaddam  M.1, Naghi A.1
 
 
 
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Ardabil Regional Educational Blood Transfusion Center, Ardabil, Iran
 
 
Abstract
Background and Objectives
Unexpected alloantibodies in the sera of patients who have a history of blood transfusion or pregnancy were found; they caused complications in a patient following blood transfusion.
 
Case
A 30-year-old woman with a history of five abortions at months 7 and 9 and with a history of 4 units of blood transfusion in one of her pregnancies referred for screening tests at the week 19th of her pregnancy. In antibody screening and genotyping, 2 cells of the 3 cells of the triple panel and 8 cells of the 11 cells of the triple panel showed positive reactions at different temperature degrees, respectively. Selected Cells and Enzyme treatment were used for the final confirmation of antibody typing.
 
 
Conclusions 
The studies show that the incidence of these alloantibodies is higher in the sera of patients who have a history of blood transfusion and recurrent pregnancies. Based on the results, it is recommended for the patients with anti-D and –E to receive blood components free of these two antigens.
 
Key words: Alloantibodies, Previous Abortion, screening
 
 
 
 
 
 
 
 
 
 
 
 
Received:  8 Jun 2015
Accepted: 9 Dec 2015
 
 
 

Correspondence: Ghezelbash B. PhD Student of Hematology & Blood Banking. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine and Ardabil Regional Educational Blood Transfusion Center.
Postal Code: 5613774111, Ardabil, Iran. Tel: (+98451) 3361408; Fax: (+98451) 3361409
                E-mail: behruzghezelbash@yahoo.com
Type of Study: case report | Subject: Blood transfusion medicine
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