A report of a Bombay phenotype case (Oh) during establishment of haemovigilance system in Bandar Abbas

Jalali Farahani, F.; Charsizadeh, E.; Mozaffari Khorgoo, Z.; Moghaddam, M.; Radmehr, R.; Faranoush, M.; Balali, M.R.; Moradi Shamami, N.; Ramezani, H.; Shahebrahimi, E.; Naderi Beni, M.

Volume 10, Issue 4 (winter 2014) Sci J Iran Blood Transfus Organ 2014, 10(4): 406-410 | Back to browse issues page

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Jalali Farahani F, Charsizadeh E, Mozaffari Khorgoo Z, Moghaddam M, Radmehr R, Faranoush M, et al . A report of a Bombay phenotype case (Oh) during establishment of haemovigilance system in Bandar Abbas. Sci J Iran Blood Transfus Organ 2014; 10 (4) :406-410
URL: http://bloodjournal.ir/article-1-832-en.html

A report of a Bombay phenotype case (Oh) during establishment of haemovigilance system in Bandar Abbas

F. Jalali Farahani ^*

, E. Charsizadeh

, Z. Mozaffari Khorgoo

, R. Radmehr

Abstract: (13889 Views)

Abstract Background and Objectives For people with Bombay phenotype due to the expression of strong IgM Anti H in their sera, transfusion with ABO group O blood will cause acute hemolytic reactions. Therefore, it is important to detect them. Case Following O blood type transfusion to a blood group O Rh positive patient with multiple trauma, acute hemolytic transfusion reaction happened. The reaction was recognized by the trained nurse in the haemovigilance system. In serologic studies, a high level of anti-H, anti-A, and anti-B was detected in the patient blood. Conclusions This case increased the number of Bombay phenotypes in Iran to 16. Therefore, using antibody screening test and existence of trained nurses and physicians with haemovigilance system in order exact management of transfusion reactions should be considered necessary.

Keywords: Key words: Blood Transfusion, Iran, Hemovigilance, Agglutination