Volume 21, Issue 3 (Autumn 2024)                   Sci J Iran Blood Transfus Organ 2024, 21(3): 224-235 | Back to browse issues page

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Chegini A, Jamalian A, Boroujerdi Alavi2 A, Maghari A. Evaluation of coagulation parameters of heart surgery patients after using intraoperative cell salvage. Sci J Iran Blood Transfus Organ 2024; 21 (3) :224-235
URL: http://bloodjournal.ir/article-1-1549-en.html
Evaluation of coagulation parameters of heart surgery patients after using intraoperative cell salvage
A. Chegini * , A. Jamalian , A. Boroujerdi Alavi2 , A.H. Maghari
Keywords: Key words: Cardiopulmonary Bypass, Blood conservation, Bleeding, Coagulation Factor
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Sci J Iran Blood Transfus Organ 2024;21 (3): 224-235
Original Article
 
 Evaluation of coagulation parameters of heart surgery
patients after using intraoperative cell salvage


Chegini A.1, Jamalian A.2, Boroujerdi Alavi A.2, Maghari A.H.3




1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Shahid Lavasani Hospital, Sorkheh Hesar, Tehran, Iran
3Department of Family Health, Social Determinants of Health Research Center, Ardabil University of Medical Sciences, Ardabil, Iran



Abstract
Background and Objectives
Bleeding management during and after surgery, including the use of cell salvage device (CS), is one of the pillars of patient blood management.The purpose of this article is to investigate the coagulation status of heart surgery patients after using the CS device.

Materials and Methods
This cohort study (three days) was conducted in the third referral hospital in July 2019 after the establishment of patient blood management. The criteria for entering the study were selecting heart surgery patients who had given informed written consent to join the comprehensive program "patient blood management". After surgery and using the CS device, the patient's vital signs, the total bleeding volume in mL from the chest tube, as well as coagulation parameters were considered in the intensive care unit after surgery for three days.

Results
In July 2019, for sixteen heart surgery patients the CS device was used, including 7 women and 9 men, with an average age of 61.36 years. Three days post-surgery, their vital signs stabilized, and no further surgical intervention was necessary. Follow-up tests revealed a significant reduction in bleeding from the first 6 hours through the end of the first day and from the second to the third day (p = 0.027). Platelet levels and PTT showed no significant changes over time (p = 0.009 and p = 0.006).

Conclusions 
The patients’ vital signs were stable after using the device in the intensive care unit, and there was no correlation between the amount of bleeding and the laboratory parameters.

Key words: Cardiopulmonary Bypass, Blood conservation, Bleeding, Coagulation Factor




Received: 21 Aug 2024
Accepted:24 Sep  2024



Correspondence: Chegini A., MD. Specialist in Anesthesiology. Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 82052256; Fax: (+9821) 88601599
E-mail: a.chegini@ibto.ir
 
Type of Study: Research | Subject: Heart and Vessels Surgeon
Published: 2024/10/1
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