Volume 21, Issue 2 (Summer 2024)                   Sci J Iran Blood Transfus Organ 2024, 21(2): 160-168 | Back to browse issues page

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Mokariani M, Mokariani Z, Amiri F, Ghadamghahi F. Correlation of red blood cell indices with CRP and IL-6 in Covid-19 patients admitted to Hamadan hospitals in 2020, 2021. Sci J Iran Blood Transfus Organ 2024; 21 (2) :160-168
URL: http://bloodjournal.ir/article-1-1531-en.html
Correlation of red blood cell indices with CRP and IL-6 in Covid-19 patients admitted to Hamadan hospitals in 2020, 2021
M. Mokariani , Z. Mokariani , F. Amiri * , F. Ghadamghahi
Hamedan University of Medical Sciences
Keywords: COVID-19, Red Blood Cells, Red Cell Indices, C-Reactive Protein
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Sci J Iran Blood Transfus Organ 2024; 21 (2): 160-168
Original Article
 
Correlation of red blood cell indices with CRP and IL-6
in Covid-19 patients admitted to Hamadan hospitals
in 2020, 2021

Mokariani M.1, Mokariani Z.1, Amiri F.2, Ghadamgahi F.3


1Student Research Commitee, Hamadan University of Medical Sciences, Hamadan, Iran
2School of Paramedicine, Hamadan University of Medical Sciences, Hamadan, Iran
3School of Public Health, Tehran University of Medical Sciences, Tehran, Iran


Abstract
Background and Objectives
The covid-19 epidemic leads to more mortality while creating health-treatment problems. Exact identification of the patients, evaluation of immunologic and hematologic parameters and their relationship is important in determining the treatment process. Therefore, this study was conducted with the aim of investigating the relationship between red blood cell indices and CRP and IL-6 in patients with covid-19.

Materials and Methods
In this descriptive-analytical cross-sectional study, the data of 280 hospitalized patients with covid-19 in 3 Hamedan hospitals during 2020 and 2021 were entered in SPSS version 27 software. Data were analyzed using Chi square test, Spearman correlation coefficient, with the significance level (p< 0.05).

Results
By evaluation of the data of covid-19 patients, it was found that Hb, Hct, MCHC, RDW, and MCV indices with correlation coefficient of 0.16, 0.19, 0.16, 0.21, and 0.23 are related to IL-6 level significantly (p : 0.007, 0.002, 0.009, < 0.001, and < 0.001, respectively). Meanwhile, none of these indices have a significant relationship with the CRP level.

Conclusions 
Accurate assessment of red blood cell indices and their relationship with immunological parameters could be helpful in term of choosing proper treatment method, predicting disease severity and clinical manifestations, determining required service level, and providing intensive care for patients.

Key words: COVID-19, Red Blood Cells, Red Cell Indices, C-Reactive Protein







Received:  22 Apr 2024
Accepted: 24 Jun 2024



Correspondence: Amiri F., PhD of Hematology & Blood Banking. Assistant Professor in Department of Medical Laboratory Sciences, School of Paramedicine, Hamadan University of Medical Sciences.
Postal Code: 6517838741, Hamadan, Iran. Tel: (+9881) 38380109; Fax: (+9881) 38381017
E-mail: f.amiri@umsha.ac.ir
 
Type of Study: Research | Subject: Hematology
Published: 2024/06/30
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