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Frequency of primary clinical manifestations of bleeding diseases in patients referred to Besat Hospital in Hamadanin 2020-2021
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R. Salimi *    , B. Zolfaghari , H. Isfahani , H. Rafieemehr |
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Abstract: (1169 Views) |
Abstract
Background and Objectives
The clinical manifestations of bleeding diseases is very important in terms of proper management and prevention strategies. The aim of this study was to determine the frequency of early clinical manifestations of bleeding diseases in Hamadan.
Materials and Methods
In this cross-sectional study, 76 patients with hemorrhagic diseases with medical records in Besat Hospital during 2020-2021 in terms of age, sex, type of hemorrhagic disease, the primary clinical manifestations, coagulation factor level, family history of hemophilia, number of blood product injections, receiving way of blood products and illness severity were evaluated. Data were analyzed using chi-square test and SPSS software version 23.
Results
The mean age of patients was 24.60 ± 15.56 years; 82.92% were male and 17.08% were female. Hematoma (18.42%), petechiae and ecchymosis (18.42%), bleeding after circumcision (18.42%), and nosebleeds(10.50%) were the most common initial manifestations. Hemophilia type A with 67.1% which was severe (66.77%), moderate (14.4%) and mild (18.83%). No significant difference between the severity of hemophilia with the initial manifestations of the disease and the type of product was observed and neither between girls and boys in terms of initial clinical manifestations.
Conclusions
In this study, the most common BDs in hemophilia occurred within the ages of 1-2 years with Glanzman syndrome the most frequent. Hematoma, petechiae, ecchymosis, and bleeding were the most common occurrences in hemophiliacs. Most of them had a severe form of the disease and in terms of type, severity, and first clinical manifestations of hemophilia the findings were almost similar to the results of other studies.
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| Keywords: Key words: Hemophilia A, Hospitals, Bleeding |
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Full-Text [PDF 430 kb]
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Type of Study: Research |
Subject:
Blood transfusion medicine
Published: 2022/07/1
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