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:: Volume 17, Issue 3 (Autumn 2020) ::
Sci J Iran Blood Transfus Organ 2020, 17(3): 226-241 Back to browse issues page
Advances and challenges in storage, transplantation, expansion and homing of Umbilical Cord Blood Hematopoietic Stem Cells (UCB-HSCs)
V. Niazi , S. Heydari Keshel Dr., M. Shahbazi
Abstract:   (831 Views)
Abstract
Background and Objectives
Umbilical cord blood hematopoietic stem cells (UCB-HSCs) have high potential capabilities in the treatment of hematological and non-hematological disorders. Awareness of biology, self-renewal, homing, expansion, storage, and transplantation can lead to optimal use of these cells.
 
Materials and Methods
In this Review article in order to investigate the advances and challenges in cord blood banks, the expansion, storage, homing and transplantation of umbilical cord blood stem cells, we used key words like umbilical cord blood, hematopoietic stem cells and stem cell banks for searching published articles in the PubMed database during 2000 to 2020.
 
Results
Over time, many advances in biology, expansion, storage, and transplantation of cord blood cells have been made by researchers around the world with a growth in the number of private and public cord blood banks in parallel. Despite these advances, there are still challenges to the optimal use of these cells.
 
Conclusions 
Increasing our awareness about the achievements and shortcomings in the area of UCB-HSCs, can lead to the formation of new strategies and further studies for the optimal use of these cells.
 
Keywords: Key words: Umbilical Cord Blood, Hematopoietic Stem Cells, Transplantation
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Type of Study: Review Article | Subject: Stem cells
Published: 2020/10/1
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Niazi V, heydari Keshel S, Shahbazi M. Advances and challenges in storage, transplantation, expansion and homing of Umbilical Cord Blood Hematopoietic Stem Cells (UCB-HSCs). Sci J Iran Blood Transfus Organ. 2020; 17 (3) :226-241
URL: http://bloodjournal.ir/article-1-1324-en.html


Volume 17, Issue 3 (Autumn 2020) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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