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:: Volume 9, Issue 4 (Winter 2013) ::
Sci J Iran Blood Transfus Organ 2013, 9(4): 463-477 Back to browse issues page
The challenges of hepatitis B in blood transfusion in Iran
N. Saki , AAl Pourfatholah , A. Dehghani Fard , SH. Mousavi , M. Kazemi Arababadi , O. Kiani Ghaleasrdi
Abstract:   (16627 Views)

  Abstract

 Background and Objectives

 Hepatitis B is one of the most dangerous causes of liver infection in the world, and the first known factor responsible for post transfusion infections (PTI). Thus, all donated units and blood products are tested for HBV. HBV genotypes are divided into eight groups with genotype D being dominant in Iran. Occult hepatitis B infection (OBI) is common worldwide and the possibility of transmission of hepatitis B infection is a cause of concern in blood transfusion centers.

  

 Materials and Methods

 The present article attempted to review articles published in association with hepatitis B and blood transfusion in Iran to show an image of hepatitis B in Iran compared to the world. 

 

 Results

 Studies done in Iran have shown varied statistics of hepatitis B infections. In thalassemics, hemodialysis patients, and intravenous drug users, 1.5%, 5.1% and 5.8% were HBsAg positive, respectively. OBI rate also varies from 0.15 to 1.5 percent. The levels of HBsAg in different reports were shown to be 0.47%, 0.41%, 0.23%, 0.4% and 1.08% among blood donors however, the rate of infection was very low in regular donors.

 

 Conclusions

 Given the importance of the screening of hepatitis B in blood donors, using sensitive diagnostic tests, especially molecular tests, for reduction in the window period is critical.

 

Keywords: Key words: Hepatitis, Infection, Blood Donors
Full-Text [PDF 444 kb]   (2466 Downloads)    
Type of Study: Review Article | Subject: Virology
Published: 2013/08/27
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Saki N, Pourfatholah A, Dehghani Fard A, Mousavi S, Kazemi Arababadi M, Kiani Ghaleasrdi O. The challenges of hepatitis B in blood transfusion in Iran. Sci J Iran Blood Transfus Organ 2013; 9 (4) :463-477
URL: http://bloodjournal.ir/article-1-726-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 9, Issue 4 (Winter 2013) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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