[Home ] [Archive]   [ فارسی ]  
:: Main :: About us :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 4, Issue 5 (Winter-blood saftey supplement 2008) ::
Sci J Iran Blood Transfus Organ 2008, 4(5): 323-329 Back to browse issues page
Prevalence of HBcAb among the HBsAg negative first-time blood donors in Khorramabad and Borujerd blood centers
J. Abdi , H.R. Moazami Goodarzi
Abstract:   (130449 Views)

  Abstract

 Background and Objectives

 This research was carried out to determine the prevalence of HBcAb among the HBsAg negative first-time blood donors who had referred to Khorramabad and Borujerd centers for blood donation.

 

 Materials and Methods

 This study was established on a descriptive cross-sectional basis in which HBsAg test (ELISA) was primarily performed on all of the donors having referred to Khorramabad and Borujerd blood centers then, out of all those referred 1000 subjects, who were first-time and HBsAg negative, were selected for furthur investigation. The information concerning age, gender, job, blood transfusion, and HBV vaccine injection was included in the questionnaire of the study. HBcAb (total & IgM) and HBsAb tests were performed on the selected donors. Data were collected and finally the prevalence rate of HBcAb was determined.

 

 Results

 The results of the study showed that out of 1000 HBsAg-negative first-time blood donors, only 47 were HBcAb+, from which 27 were HBcAb (total)+, and 3 were HBcAb (IgM)+. 18 were both HBsAb+ and HBcAb+, and 53 were seropositive only for HBsAb.

 

 Conclusions

 It was demonstrated that the first-time blood donors who are seronegative for HBsAg marker will be easily identified through HBcAb test if they are in the so-called core window period of the virus. Meanwhile, this group of donors have been implicated as high-risk for transfusion-transmitted HBV infection. So, detecting this marker will remarkably reduce the chance of latent cases of HBV infection and help promote blood safety.

 

 Key words : Blood donor, Hepatitis B, Iran

Keywords: Blood donor, Hepatitis B, Iran
Full-Text [PDF 205 kb]   (3547 Downloads)    
Type of Study: Research | Subject: Infectious disease
Published: 2014/08/17
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Abdi J, Moazami Goodarzi H. Prevalence of HBcAb among the HBsAg negative first-time blood donors in Khorramabad and Borujerd blood centers . Sci J Iran Blood Transfus Organ. 2008; 4 (5) :323-329
URL: http://bloodjournal.ir/article-1-201-en.html


Volume 4, Issue 5 (Winter-blood saftey supplement 2008) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
Persian site map - English site map - Created in 0.06 seconds with 31 queries by YEKTAWEB 4274