Showing 16 results for Risk
L. Kasraian, S.a. Torabi Jahromi,
Volume 1, Issue 1 (11-2004)
Abstract
Abstract
Background and Objectives
Some blood donors may donate blood for being informed of their HIV test results such people are threats to blood and its derivatives.
Materials and Methods
This study was a cross-sectional study using four choice questionnaires which were distributed among 20800 blood donors who had referred to Shiraz Blood Transfusion Organization. The sample was selected using systematic random sampling. Questionnaire included three parts: part one contained demographic characteristics of donors, part two reasons motivating them to donate blood, and three risk factor of HIV if donation occures for HIV checkup. Chi square and regression analysis were used to analyze the data.
Results
The average age of donors was 34.46 ± 11.3. 87% of donors were male and 12.3% female 51.8% were married and 48.2% single. 36.3% were first time blood donors and 63.7% had more than one time blood donation record the average number of blood donation attempts among these subjects was 6.7 ± 3.2. 61% of them were tested for HIV in routine tests. Totally, 14.8% of these subjects had donated blood for HIV checkup. Blood donation for HIV checkup was more frequent in males, singles and first time donors (P<0.05). There was no correlation between occupation, education status, age and blood donation and HIV checkup (P>0.05). Risk factors of those who had donated blood for HIV tests were identified to be sexual contacts (38.3% of subjects), contacts with HIV suspicious people (18.7%), intravenous drug users (3.7%), and tatooing (2.8%). The rest 36.5 percent had no known risk factors.
Conclusions
14.8% donate blood for HIV checkup in this study and could threaten the blood supply. The most common risk factor in those who referred for HIV checkup was sexual contact with
high-risk partners. Blood donors should receive suitable training for providing safe blood. To this end, they must feel accountable for their blood donation.
Key words:
B. Ataei , M.r. Khademi , A. Mirmohammad Sadeghi , Z. Nokhodian , N. Kasaeian ,
Volume 2, Issue 5 (9-2005)
Abstract
Abstract
Background and Objectives
Viral hepatitis B is a dangerous disease with high mortality and morbidity rate in the world. It has been proved that its prevalence in different areas depends on risk behaviors and people’s awareness level. This paper was prepared to detect the risk factors of hepatitis B in blood donors in Isfahan province.
Materials and Methods
In a cross-sectional study, 39 seropositive blood donors and 261 seronegeative ones in 2004 were studied. HBsAg was examined via ELISA. Standard hepatitis B risk factor questionnaires were completed for all of the samples and the prevalence of each risk factor in case and control subjects was compared through X2 test, using SPSS-10 software with p<0.05.
Results
This study indicated that the history of surgeries, use of shared razors, jaundice of mother, presence of HBsAg+ patients and drug addicts in families were statistically significant in the two groups. There was not any hemodialysis history, accident of needle sticks and needle sharing by drug addicts.
Conclusions
Since the relative frequency of surgery history in the two groups was significantly different, attending to hospital and operation room hygine seems to be very important. Moreover, since hepatitis B can be prevented with education and vaccination, the families of
HBsAg+ patients and drug addicts should be encouraged to use education and vaccination.
Using the results of this study, it is necessary to pay attention to hospitals and raise people awareness about hepatitis B transmission routes and vaccination of high risk individuals.
Key words: Hepatitis B, Risk factors, Blood donors, Isfahan
Shila Ghafari, Fereshteh Majlessi, Abbas Rahimi Foroushani, Mahtab Maghsudlu,
Volume 3, Issue 4 (1-2007)
Abstract
Abstract
Background and Objectives
The complications of blood donation are the first reasons why donors do not return for further blood donation attempts. This study was designed to determine the frequency of these complications and their associated risk factors among blood donors in Tehran. It also aimed to provide suitable methods to decrease the frequency of adverse reactions of blood donation, thus eliminating the most important causes of nonreturn, while ensuring the health of donors.
Materials and Methods
This analytical descriptive cross-sectional study was performed on 554 blood donors who had donated blood from February 2004 through September 2005 in four fixed blood donation bases and four mobile blood collection buses. Each base was considered as a stratum, and a stratified random sampling proportional to size was done to select the donors.
Results
Reported results showed donor reaction rate of 26%, with ecchymosis (22.7%), pain (8.5%), tenderness (5.6%), and hematoma (5.1%) as the most common. The frequency of donor complications has a significant statistical correlation with manner of needle entrance in vein, lack of change in needle position under skin, prolonged phlebotomy, incomplete phlebotomy, and hard work with hand within 12 hours after donation.
Conclusions
Regarding the frequency values derived from different complications, it can be concluded that attention to these complications and their control can help encourage donors to become repeat donors preventing their lack of return for further blood donation.
�
Key words : Complications, Blood donation, Risk factors�
M.r. Deyhim, F. Razjou, M. Maghsudlu, M. Abedini,
Volume 4, Issue 4 (2-2008)
Abstract
Abstract
Background and Objectives
Venous thrombosis is one of the important causes of morbidity and mortality all over the world. Elevated plasma homocysteine is known as a cause of vein morphology changes and endothelial dysfunction which lead to platelet activation, fibrinolysis inhibition and finally atherothrombosis. In this study, we evaluated the role of homocysteine in atherothrombosis as compared to the control group with no history of thrombosis.
Materials and Methods
In this case control study‚ 100 patients with arterial thrombosis (54 men and 46 women) as the case group and 68 as control (40 men and 28 women) were involved. Blood samples were taken in the EDTA-located tube and transported to the laboratory for fasting plasma homocysteine to be measured by ELISA kits. Some data such as age, sex, thrombosis history, and familial thrombosis history were taken from the patients through a questionnaire. We measured fasting plasma homocysteine in both case and control groups by ELISA method. The statistical analysis was performed by SPSS statistical software using T-Test and Chi-square odds ratio was also calculated.
�
Results
The average rates of homocysteine in the case and control group were 23.85 ± 18.4 and 11.48 ± 3.4 µmol/lit respectively showing statistical significance. The hyperhomocysteinemia frequency in the case group was 48%, whereas 17.6% in the control. A significant difference was also observed in the frequency of hyperhomocysteinemia between male (70.4%) and female (21.7%) in the case group. There was a moderate correlation between homocysteine level and age in the case group.
Conclusions
According to the achieved odds ratio (2.72), hyperhomocysteinemia is an independent risk factor for thrombosis. It means that homocysteine measurement should be determined in thrombosis-affected or high risk patients. Dietary supplementation with low doses of folate and vitamin B12 should be considered in affected persons.
�
Key words : Homocysteine, Venous thrombosis, Risk factor
Mohammad Reza Tabatabie, Azita Azarkeivan, Minoo Ahmadinejad, Mehdi Karbasizadeh, Farzaneh Tavasolo, Abdolmajid Tolabi, Mahtab Maghsudlu,
Volume 5, Issue 3 (9-2008)
Abstract
Evaluation of elevated FVIII in patients with thrombophilia
Tabatabaie M.1(MS), Azarkeivan A.1,2(MD), AhmadiNejad M.1(MD), KarbasiZadeh M.1(DMT),
Tavasoli F.1(BS),Toolabi A.M.1(MD), Maghsudlu M.1(MD)
1Iranian Blood Transfusion Organization-Research Center, Iran
2Thalassemia Clinic,Tehran,Iran
Abstract
Background and Objectives
Thrombus formation may form enhanced coagulation or impaired fibrinolysis. An increased tendency for the blood to clot is referred to as the hypercoagulable state or thrombophilia which includes various inherited and acquired clinical disorders or mixed conditions. There are many studies suggesting that elevated factor VIII may be a common and independent risk factor for thrombotic events. We tried to assess the level of factor VIII in patients with idiopathic thrombosis.
Materials and Methods
Our cases were the patients with idiopathic venous thrombosis having referred for hypercoagulable studies to Coagulation Lab in Iranian Blood Transfusion Organization. The inclusion criterion was the occurrence of thrombotic event confirmed by objective diagnostic methods coupled with three months of follow-up without any other disorder. Our controls were from healthy blood donors and matched with the cases on sex, ethnicity, and age. Plasma of a healthy person was used to establish the normal reference range according to which our patients are compared. Factor VIII levels were measured using a one-staged assay, the PTT based Diagonistica Stago on the STA compact automated coagulation factor analyzer. SPSS and Chi-square were finally used for data analysis.
Results
One hundred fifty two cases and 130 controls enrolled. The mean factor VIII level for cases was 157.26 IU/dl (SD±53.8) with the minimum level of 66 and maximum of 364 IU/dl. For controls, the mean factor VIII level was 111.78 IU/dl (SD± 29.68) with the minimum level of 42 and the maximum of 195 IU/dl. These levels were statistically significant and higher in the case group. The elevated FVIII level was higher in females than males (35.3% vs 23.8%) and increased with age. The normal range in the control group varied within 52-171 IU/dl, which is higher than the normal level of 50-150 IU/dl.
Conclusions
There are many studies showing that increased FVIII level may be an independent risk factor for thrombosis. Our results suggested elevated FVIII level in 28.9% of the patients with thrombosis compared to 3.1% in the control group. So, factor VIII measurement is recommended to be practiced in routine thrombophilia screening programs.
Key words: Thrombosis, Factor VIII,Venous thromboembolism, Risk factor, Thrombophilia
SJIBTO 2008 5(3): 149-156
Received: 15 Dec 2007
Accepted: 9 Jul 2008
Correspondence: Azarkeivan A., Pediatric Hematology Specialist. Iranian Blood Transfusion Organization-Research Center.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821)88601599 Fax: (+9821)88601599
E-mail: azarkeivan@ibto.ir
Dr. Gh. Tabrizi, M. Vatankhah, S. Tabrizi,
Volume 6, Issue 4 (1-2010)
Abstract
Abstract
Background and Objectives
Acquired Immune Deficiency Syndrome (AIDS) has social, psychological, and biological consequences thereby changing it into a phenomenon that could threaten mental health of society and even those affected. Thus, in the present research we have aimed to study the two-way impacts of personality disorders and AIDS in patients exposed to high-risk behaviors.
Materials and Methods
The main purpose of this research is to perform a comparative study of personality and psychological disorders among HIV positive and negative individuals. Consequently, 60 people were selected as the sample group from whom 30 were the ones under treatment in Mashad Consultation Center for Infectious Diseases and Behavioral Disorders the others were 30 non-infected people who were selected randomly. They all were assessed by means of the Millon Clinical Multiaxial Inventory–II. The obtained data were finally analyzed by the use of T-test and Man-withney test.
Results
The results displayed the fact that HIV positive individuals compared with HIV negative ones suffered a higher level of emotional and behavioral disorders in their lifetime. Schizotypal personality, borderline disorder, paranoid, anxiety, dysthymia, alcohol and drug dependence, thought disorder, major depression and delusional disorder were the problems investigated.
Conclusions
Unfavorable procedures of psychological growth can impair the personality development thereby making people susceptible to being infected with disease provoking factors including AIDS being affected with AIDS in turn can act as an effective variable in emergence of emotional and psychological impairments.
Key words : Personality Disorders, HIV, AIDS, High risk behavior�
Dr. H. Faramarzi, P. Bagheri, N. Rahimi,
Volume 8, Issue 3 (8-2011)
Abstract
Abstract
Background and Objectives
Thalassemia major is one of the most common genetic blood disorders that passes from parents to children . Since Fars province is one of the most common locations of thalassemia in our country. It seems that the present study can be helpful by identifying main non-clinical factors of the disease.
Materials and Methods
This cross sectional study was done on registered data of less than 12 year old major thalassemia patients in Fars province by census method in 1997-2010 . Underlying causes of thalassemia are divided into three groups: S1 cases due to hardware problems, S2 cases due to parents carelessness without having a history, and S3 patients born to parents who married when genetic tests were not routine. Data were analyzed by using SPSS16 and ANOVA tests.
Results
Analysis showed that S1 with 48 persons (15.38%)`with the mean age of 5.6 ± 3.2, S2 with71 persons (22.75%) with the mean age of 6.8 ± 1.2, and S3 with193 person (61.85%) with the mean age of 8.8 ± 3.30 were the main groups of thalassemia . The least incidence rate was 0.13 per 10000 in 2010 .
Conclusions
With identifying the main underlying causes of major thalassemia regardless of its main cause which is herediatry from parents, considering levels and different consequences of these causes, and high efficiency of genetic tests before marriage, effective steps can be taken to reduce health-social and economic problems of thalassemia.
A.a. Abdollahi, Dr. M. Ghorbani, H. Asayesh, M. Nouroozi, M. Mansourian,
Volume 8, Issue 4 (1-2012)
Abstract
Abstract
Background and Objectives
Cardiovascular disease (CVD) is a common cause of morbidity and mortality. The relationship between ABO blood groups and main risk factors of CVD is unknown. So this study was designed to investigate whether there is an association between ABO blood groups and cardiovascular risk factors in healthy population.
Materials and Methods
In this cross-sectional study, risk factors screening for CVD on 2920 healthy individuals of Golestan province in 2005 were estimated by a questionnaire that aimed to extract information about age, sex, physical activity, smoking, blood group type, weight, height, blood pressure and family history of CVD. Data were analyzed with SPSS13 and by using Chi Square and ANOVA tests.
Results
Out of the total number of 2920, 57.4% were male, 70% inactive, 14% smoker, 25% hypertensive, 23% obese, and 21% had family history of CVD with the mean age of 41.52 ± 12.317. Blood groups O (32.9%), A (30.1%), B (23.3%) and AB (13.7%) were the most frequent ones, respectively. Amongst cardiac risk factors, it was only the frequency of family history of CVD that varies across different blood groups, and individuals with A blood group reported to have a more frequent family history of CVD as compared with other blood groups.
Conclusions
These findings illustrate amongst cardiovascular risk factors only family history of CVD as having a significant correlation with ABO.
Dr. M. Samadi, Dr. A.h. Ghasemzade, Gh. Sarizade, Dr. S. Ebrahimi, Sh. Saati, A. Abassinejad-Pour, Dr. L. Nazar Ardekani,
Volume 10, Issue 4 (1-2014)
Abstract
Abstract
Background and Objectives
Selection of healthy blood donors is an important process to identify high risk volunteers. Monitoring and evaluation of the deferral procedure is of the highest importance to balance blood availability and safety. The aim of the current study was to compare the prevalence of HBV, HCV and HIV serologic markers between deferred donors and eligible blood donors to assess the value of the current donor selection process.
Materials and Methods
Six hundred and nineteen voluntary blood donors in Ahvaz city were included. Serum samples from deferred and eligible donors were examined for serologic markers of HBV, HCV, and HIV using enzyme-linked immunosorbent assay. All positive samples were confirmed using confirmatory tests.
Results
The prevalence rates of HBV infection among deferred and eligible blood donors were estimated to be 0.5% and 0.2%, respectively. Anti-HCV reactivity was detected among 1.3% of deferred blood donors. Moreover, the prevalence of anti-HIV among deferred and eligible blood donors was 0.2% and 0.05%, respectively. We found that the overall prevalence rates of HBsAg, anti-HCV, and anti-HIV in the deferred blood donors are significantly higher than those in the eligible blood donors.
Conclusions
The results of this study indicate the high prevalence rate of blood borne infections. Moreover, it seems that the current donor selection process is effective to identify healthy blood donors. However, the effectiveness of some of the currently used deferral questions in reducing viral risks warrants further study.
Dr. H. Ebrhimipour, Y. Molavi Taleghani, Dr. A. Vafaee Najar, Dr. S.h. Sayedin, M. Vejdani,
Volume 11, Issue 4 (1-2015)
Abstract
Abstract
Background and Objectives
Pediatric emergency departments are high-risk areas in the healthcare setting and blood transfusion is known as the unique clinical measure. This study aims to investigate the prospective risk assessment of blood transfusion in the Pediatric Emergency Department of Ghaem Hospital by the Health Failure Mode and Effects Analysis (HFMEA) methodology.
Materials and Methods
A mixed method ) quantitative and qualitative analysis ( was used to analyze failure modes and their effects with HFMEA. For identify and analysis, the potential errors of the transfusion process were used by the “Health Failure Mode and Effects Analysis (HFMEA)” methodology. The study was undertaken using a consensus development panel to which the HFMEATM process was applied.
Results
The HFMEA team identified 8 processes, 24 sub-processes, and 77 possible failures. Thirteen failure modes (hazard score >= 8) were identified and entitled as "failures with non-acceptable risk” and were moved into the decision tree. Among the influencing factors, the most common reasons for error were related to educational factors (27.2%), and the less common reasons for error to patient factors (2%). Action types were classified as acceptance (11.6%), control (74.2%), and elimination (14.2%).
Conclusions
Applying the re-engineering process for the required changes, standardizing and updating the blood transfusion procedures, detecting the root causes of blood transfusion adverse events, using patient identification bracelets, providing training classes and educational pamphlets to raise awareness of the personnel, and holding the monthly transfusion medicine committee have been considered as practical strategies in the work flow of Ghaem Hospital.
P. Mohammadi, S. Soleimani, Dr. Z. Sharifi, Dr. A. Nouruzi, Dr. M. Najafi,
Volume 11, Issue 4 (1-2015)
Abstract
Abstract
Background and Objectives
Polymorphonuclear cell-derived myeloperoxidase (MPO) is a known agent in the progression of inflammatory disorders via the production of reactive oxygen species. In this study, we investigated the association between rs2333227 polymorphism (G-436 A) within the MPO gene promoter and coronary artery stenosis.
Materials and Methods
A total of 160 Iranian subjects (patients = 86 and controls = 74) were introduced on the basis of the study criteria. DNA was extracted from white blood cells and the genotype distribution was evaluated by PCR-RFLP technique .
Results
The AA, AG and GG genotype frequencies in study population were calculated to be 6.90%, 39.4% and 53.7%, respectively (p > 0.21). There was no significant difference between the genotype distribution and the extent of coronary stenosis in patients with 1VD, 2VD and 3VD (p = 0.71). The A allele frequencies were 25.6% and 27.4% in patients and controls, respectively.
Conclusions
In general, our results indicate that the Iranian population genotype and allele distribution do not play a role in the development and severity of coronary artery disease.
Dr. M. Alaei, Dr. M. Zadsar, A. Aghai , Dr. E. Pouriani,
Volume 16, Issue 4 (12-2019)
Abstract
Abstract
Background and Objectives
HBV, a classic viral Transfusion Transmitted Infection(TTI), is considered an important health and blood safety issue in every society. Prevalence of HBsAg positivity is variable among Iranian blood donors nationwide. This study was performed to determine the frequency of HBsAg positive blood donors and the probable associated risk factors in Mazandaran province in 2013.
Materials and Methods
In this cross sectional descriptive study, demographic and donation data were gathered from IBTO data base (NEGARE). HBsAg positive donors were recalled for post test counseling and assessment of probable risk factors. SPSS 16 Chicago, χ2 and T-test were used as tools for data analysis.
Results
Among 131950 whole blood donors with mean age of 31.1 ± 9.5, 174(0.13%) proved to be HbsAg positive. Deferral rate was 16.6%. The highest and lowest positivity rates were observed at Babol and Galoogah, respectively. 95% of positive cases were detected among first time and male donors (p = 0.0001). Older age, lower education level, and first time donation were obtained as demographic risk factors primarily. No significant association between gender and marital status was found. However, post test counseling revealed non-immune dental procedures, high risk sexual contacts, cupping, family history of Hepatitis, hospital admission, tattooing, history of surgery, Intravenous Drug Use (IDU), endoscopic procedures, transfusion history and needle stick as risk factors in HBsAg positive donors.
Conclusions
HbsAg positivity rate in Mazandaran province donors is compatible with the country rate (0.13%). Main risk factors except gender and marital status are almost similar to other studies.
S. Mohammadi, Dr. M.s. Karimian, S. Khodakarimi, S. Babahajiyani, A. Pourali, S. Vafaei,
Volume 19, Issue 1 (3-2022)
Abstract
Abstract
Background and Objectives
Risk is a combination of the likelihood of an incident occurring and the severity of the consequences if that incident were to occur. The aim of this research is to identify and evaluate the risk factors in the blood donation process in a fixed blood collection center of Saqez city by failure mode and effects analysis (FMEA).
Materials and Methods
It is a descriptive-applied study that was performed in a fixed blood collection center of Saqez in 2020. The researcher collected and analyzed the data using FMEA worksheets. Then the risk priority number is obtained by multiplying the three indicators of failure severity (S), the failure probability of occurrence (O), and the failure detection (D). Finally, the priority was based on the failures.
Results
Finally, 30 sub-processes were identified, of which 20 sub-processes with acceptable risk and 10 sub-processes with unacceptable risk were identified. The highest identified risk is related to the donor not paying attention to safety points before and after blood donation with a priority risk number of 168 and the lowest is attributed to the shaker not alarmed when the blood donation process ends with a RPN of 48.
Conclusions
Many of the failures identified will be reduced or eliminated by training, providing up-to-date equipment, and changing procedures and working methods.
َa. Babazadeh Rafiei, Dr. T. Sohrabi, Dr. M. Motamedi, Dr. M.h. Darvish Motevalli,
Volume 20, Issue 2 (7-2023)
Abstract
Abstract
Background and Objectives
Identifying blood supply chain risks can be effective to avoid failures that may affect the entire supply chain. The purpose of this research is to identify and rank the risks affecting the blood supply chain in the Corona virus pandemic.
Materials and Methods
In this study, 37 risks were identified based on the background of the research and interviews with 7 experts who had management positions in blood centers. Then, by distributing a researcher-made questionnaire among 113 employees of blood centers, the probability of occurrence and the severity of the impact of risks on the variables and value of each risk were calculated, and 21 critical risks were selected by using the risk matrix. Finally, the risks were weighted and ranked by pairwise comparison method using Expert Choice 11 software.
Results
The results showed that the level of blood collection with a weight of 0.417 bears the highest risk in the blood supply chain. Risks of blood collection planning error (weight = 0.192), failure to comply with safety during blood donation (weight = 0.124), inaccurate information and creating false excitement (weight = 0.09), planning error demand (weight = 0.072) and blood shortage (weight = 0.072) ranked first to fifth.
Conclusions
The level of blood collection and as a result the amount of bloodstock bears the greatest risk in the corona pandemic, which can be largely avoided by planning for appropriate information sharing and preventing the creation of false emotions. This can greatly reduce negative effects on the blood supply chain.
Dr. L. Kasraian, Dr. N. Naderi, Dr. M. Farahangiz, Dr. H. Abdorahimzadeh,
Volume 20, Issue 4 (12-2023)
Abstract
Abstract
Background and Objectives
Blood transfusion is a major challenge in treating trauma patients. This study investigated blood transfusion rates and related factors in trauma patients.
Materials and Methods
This retrospective cross-sectional study analyzed 849 trauma patients admitted to a trauma center in Shiraz, Iran during 2019-2021. Blood components usage and its relation to demographics, clinical status, lab values, and ABC score were assessed. The frequency of massive blood transfusion and the average number of blood units and blood components consumed in these patients were surveyed. Data were analyzed by T-test, Chi-squared test, and logistic regression with SPSS-23.
Results
The mean age was 38.6 ± 19.40 years and 80.9% were male. The mean blood units, platelets, and plasma used were 5.74 ± 4.57, 1.21 ± 4.87, 2.73 ± 4.32, respectively. 62.01% received massive transfusion with mean blood, platelets, and plasma units used being 8.17 ± 5.21, 3.92 ± 4.88 and 1.85 ± 6.01, respectively. Blood use correlated with systolic/diastolic pressures, blood sugar, lymphocyte count, pH, bicarbonate, base deficit, and hematocrit. 13.3% had positive ABC score and received more blood products (p < 0.001).
Conclusions
Blood transfusion in trauma patients depends on various clinical and lab factors. Identifying high-risk patients requiring urgent blood transfusion and rapid preparation of blood products is vital for optimizing trauma patient management and outcome.
Dr. E. Yazdandoust, Dr. S. Amini-Kafiabad,
Volume 21, Issue 1 (3-2024)
Abstract
Abstract
Background and Objectives
Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare and fatal complication caused by blood transfusion. In this condition, donated lymphocyte cells attack host tissues. In this review article, the history, prevalence, pathogenesis, clinical symptoms, risk factors, diagnostic methods, strategies to reduce its occurrence, prognosis, disease management, and laboratory characteristics of this condition are discussed.
Materials and Methods
For this purpose, a search was made using published reliable research in Google Scholar, PubMed, and MEDLINE databases and the findings of more than 70 articles were cited.
Results
The following study showed that live T lymphocytes from donated blood products and the resulting cytokine storm play a role in the occurrence of this complication. The symptoms of this disease appear in the form of skin rash, pancytopenia, and fever, and its diagnosis is based on clinical symptoms and laboratory findings of skin biopsy, increased liver enzymes, confirmation of lymphocyte chimerism using STR-PCR, and determination of the HLA phenotype of lymphocytes and FISH method. This complication has a higher prevalence in populations with high genetic similarity or people with immune deficiencies, however, it also occurs in other people who do not have these conditions or who have partial donor-recipient HLA matching (one-way HLA matching).
Conclusions
This complication is one of the fatal complications caused by blood transfusion that occurs within 2 to 30 days after blood products transfusion; the typical cases are associated with more than 90% mortality and mild or atypical cases have longer survival and are associated with a better prognosis that may go undetected or be treated spontaneously.
