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Showing 9 results for Key Words: Blood Donors

Dr. Hr. Saber, Dr. Sm. Mirrezaie, Dr. B. Hajibeigi, A. Abasian, A. Salek Moghadam, Dr. S.m. Alavian, Dr. H. Abolghasemi, H. Mehrabadi,
Volume 9, Issue 3 (10-2012)
Abstract

  Abstract

 Background and Objectives

 Recently a method was used for estimation of incidence rates for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) among first-time donors. Since there are no published data for HIV and HCV incidence rate estimation in Iran, we planned the present study.

 

 Materials and Methods

 In this retrospective study, all first time blood donors (98810 donors) in two age categories (17-20 and 26-33 years old) were included for analysis. To estimate HIV and HCV prevalence rates in these age groups, the total confirmed positive test results for HIV and HCV were divided by the number of all donors at the same age group. To determine the incidence of HCV and HIV, the prevalence differences at the age groups were divided by the average age differences of the relevant groups. Data were analyzed by SPSS 19.5.

 

 

 Results

 For HIV, incidence estimates were 1.47 and 1.21 per 100000 donations in 2009 and 2010, respectively (the average 1.37 per 100000 donations for 2 years of study). For HCV, incidence estimates were 15.69 and 11.83 per 100000 donations in 2009 and 2010 (the average 13.26 per 100000 donations for 2 years of study).

 

  

 Conclusions

 Data showed that the incidence rate of HIV of blood donors is comparable to developed countries, but HCV incidence rate is higher than that of developed countries. As a matter of fact we should manage blood safety by applying other technics like NAT.

  

  


Dr. M. Narimani, Dr. S. Sadeghieh Ahari, A. Esmaili Nejad, E. Soleimani,
Volume 10, Issue 2 (6-2013)
Abstract

  Abstract

 Background and Objectives

 The health systems all around the world are concerned about provision of safe and adequate blood. The blood donation, as a favorable social behavior, is affected by human characteristics. The present study attempted to investigate the altruistic behavior, empathy and social responsibility in two groups: voluntary versus non-voluntary blood donors.

  

 Materials and Methods

 The present research is a cross-sectional comparative study having included all male voluntary blood donors in Ardabil Blood Center 30 voluntary blood donors and 30 non-voluntary were randomly selected. The altruism questionnaire, empathy scale, and personality questionnaires were used as instruments and the data were collected. The research data were analyzed using Pearson correlation coefficient and multivariate variance analysis (MANOVA).

 

 Results

 The results show that the mean rates of social responsibility in voluntary and non-voluntary groups are 28.93 ±4.13 and 24.13 ±3.68 , respectively. The variables of altruistic behavior, empathy and social responsibility are estimated to be higher in voluntary than non-voluntary donors. Also there is a positive significant relationship among altruistic behavior, empathy and social responsibility variables.

  

 Conclusions

 Altruism, empathy and social responsibility are more motivating in voluntary blood donors than in non-voluntary. Therefore, to promote blood donation it would be helpful to recognize and engage people enjoying empathy, social responsibility, and altruism.

  


Dr. M. Samadi, Dr. A.h. Ghasemzade, Gh. Sarizade, Dr. S. Ebrahimi, Sh. Saati, A. Abassinejad-Pour, Dr. L. Nazar Ardekani,
Volume 10, Issue 4 (1-2014)
Abstract

Abstract Background and Objectives Selection of healthy blood donors is an important process to identify high risk volunteers. Monitoring and evaluation of the deferral procedure is of the highest importance to balance blood availability and safety. The aim of the current study was to compare the prevalence of HBV, HCV and HIV serologic markers between deferred donors and eligible blood donors to assess the value of the current donor selection process. Materials and Methods Six hundred and nineteen voluntary blood donors in Ahvaz city were included. Serum samples from deferred and eligible donors were examined for serologic markers of HBV, HCV, and HIV using enzyme-linked immunosorbent assay. All positive samples were confirmed using confirmatory tests. Results The prevalence rates of HBV infection among deferred and eligible blood donors were estimated to be 0.5% and 0.2%, respectively. Anti-HCV reactivity was detected among 1.3% of deferred blood donors. Moreover, the prevalence of anti-HIV among deferred and eligible blood donors was 0.2% and 0.05%, respectively. We found that the overall prevalence rates of HBsAg, anti-HCV, and anti-HIV in the deferred blood donors are significantly higher than those in the eligible blood donors. Conclusions The results of this study indicate the high prevalence rate of blood borne infections. Moreover, it seems that the current donor selection process is effective to identify healthy blood donors. However, the effectiveness of some of the currently used deferral questions in reducing viral risks warrants further study.
L. Montazeri Takhti, Dr. H. Eslami, Dr. A.m. Mazidi,
Volume 13, Issue 1 (3-2016)
Abstract

Abstract

Background and Objectives

Despite the advances in science and technology, the need for safe blood still remains as the priority and no suitable substitute for human blood has been discovered yet. This study aimed to investigate the attitude of blood donors towards Iranian Blood Transfusion Organization in Bandar Abbas, Iran. To do this, we have used a questionnaire to ask donors about the publicity and dissemination efforts of IBTO.

Materials and Methods

A descriptive survey research method was used and the collected data was analyzed using SPSS-19 software and Pearson and Regression tests.

Results

The blood donors’ age range was between 18 and 60 years. Donor’s age had no significant correlation with attitudes towards the publicity and dissemination efforts of IBTO (r = 0.048, p = 0.283). There was a significant correlation between the attitude towards the publicity and dissemination efforts of IBTO and “paying attention to the publicity stuff” (r = 0.148, p = 0.001). There was a significant correlation between the attitude towards the publicity and dissemination efforts of IBTO and “Social participation” (r = 0.191, p = 0.001). There was a significant correlation between the attitude towards the publicity and dissemination efforts of IBTO and “social trust” (r = 0.090, p = 0.04).

Conclusions

Out of the participants, 81.1% were found to be prompted to become blood donors via the publicity and dissemination efforts of IBTO which has had a great role in attracting people attention. The media with extensive publicity, such as television, has had more effectiveness.


Z. Daneshvar, Dr. N. Amirizadeh, Dr. A. Oodi, S. Goudarzi ,
Volume 15, Issue 2 (6-2018)
Abstract

Abstract
Background and Objectives
Detection of weak D blood type can lead to the saving of RhD negative blood components and can reduce RhIG consumption. Therefore, determining the frequency of weak D alleles in our country is necessary.
 
Materials and Methods
In this descriptive study, a total of 105 blood samples with weak expression of D antigen from 21 provinces among Iranian blood donors were studied. The phenotype of samples was tested for Rh D, C, c, E and e antigens by routine serological methods. Weak D variants were evaluated by PCR-SSP, RFLP and DNA sequencing methods.
 
Results
Among 105 weak D samples, 9 weak D alleles and 2 partial D alleles were found. The most prevalent weak D type in our population was weak D type 15(38.1%), weak D Type 1(10.48%), Type 5(7.62%), Type 4 (4.76%), Type 80 (3.8%), Type 3 (1.9%) and Type 11 , Type 8 , Type 100 each (0.95%) and Partial D DLO (8.57%), and partial D V a /DAU (0.95%). We also observed the correlation between weak D type 15 and E antigen and weak D type 1 and Partial D DLO and C antigen.
 
Conclusions 
There is a significant difference between the prevalence of Weak D variants among our blood donors compared to European and American white populations with a high incidence of weak D 1, 2 and 3, equally compared to African population with a high incidence of Partial D and weak D type 4, as well as Asian population with a high prevalence of Del.
 
 

Dr. M. Nouri, Dr. M. Maghsudlu, Dr. K. Etemad,
Volume 15, Issue 4 (12-2018)
Abstract

Abstract
Background and Objectives
The goal of Iranian Blood Transfusion Organization (IBTO) is to provide safe blood and blood components that are necessary for patients. Blood donors are interviewed and selected in order to providing  safety of blood donors and recepients, so a number of potential blood donors to be deferred. The aim of this study was to determine the rate of donors return after temporary deferral in the center of East Azerbaijan province.
 
Materials and Methods
In this study, temporary deferred donors in Tabriz in 2013 were included. Temporary deferred donors were analyzed by the reasons of deferral. The return rate during 3 years after deferral were calculated and compared between different blood donors.
 
Results
Of all the 66176 volunteers, 20% were deferred from blood donation and 80% were found eligible. Of those deferred, 92% were temporarily deferred. The most frequent causes of temporary deferral were abnormal finding in physical examinations (25%), a history of medication use (23%),  and a history of bloodletting or tattooing (8%). Of the potential fisrt time donors deferred, only 1.5% returned for blood donation during the three years following the temporary deferral. However, 54% and 94% of the repeat and regular donors returned, respectively.
 
Conclusions 
The present study showed that first-time blood donors who were deferred have a less return rate than regular and repeat donors who were deferred.
 

Dr. H. Hatami, Dr. M. Maghsulu, Dr. M.r. Balali, Dr. M.m. Seyfi Targhi,
Volume 16, Issue 1 (3-2019)
Abstract

Abstract
Background and Objectives
Iranian Blood Transfusion Organization, to maintain the health of blood donors and recipients, defines the eligibility criteria for conducting blood donation process without which blood donors are deferred. Previous studies have shown the necessity of deferral criteria for blood safety. This study showed that deferral of these volunteers has improved the health of blood donors; it has been determined based on the frequency of both positive confirmatory screening test results in blood donors on their return and temporary deferral rates especially due to high risk behaviors.
 
Materials and Methods
The study was cross-sectional descriptive. Data collection was performed based on all the data of blood donation volunteers included in the NEGAREH software. The data were then analyzed by Chi-square and Excel software.
 
Results
Out of 6,877,627 volunteers during 2012-2014, 1,416,791 volunteers were deferred from blood donation. The prevalence of infectious markers in blood donors was 0.19% (10354 donations); the prevalence was 0.018% in 2,784,593 donations of donors on return (493 donors); and for 465594 donations of deferrals it was 0.209% (975 donors). The prevalence of infectious markers for donations on return was 0.225% (211 donations) for risky behaviors and 0.205% (764 donations) for the other deferred donors.
 
Conclusions 
It has been shown that the prevalence rate of the confirmed screening test results for Transfusion Transmitted Infections especially HBSAg is higher in repeat and regular donors once temporalily deferred (particularly for high risk behaviors) and returned for donation than those without the deferral record; it shows their deferral has been effective in improving blood safety.
 

Dr. Leila Kasraian, ِdr. Neda Negarestani, Dr. Masoud Torabi,
Volume 16, Issue 4 (12-2019)
Abstract

                                    
Abstract
Background and Objectives
Informing and counseling donors with positive Transfusion Transmitted Infection (TTI) is essential for preventing them from donating blood in future, and starting treatment for reducing complications. So, we evaluated the referral of reactive donors.
 
Materials and Methods
This cross sectional study was conducted in Shiraz Blood Transfusion Center over a period of 2.5 years involving 214 reactive donors. The reactive donors were informed by three time telephone calls, one letter, and another telephone call in case of non-return. A trained counselor informed donors regarding abnormal tests and advised to refer to the respective disease clinics of the hospital for further management. The response rate of TTIs reactive donors after notification of their abnormal test results was surveyed according to the demographic status.
 
Results
Of the 214 TTIs marker-reactive donors, we did not access 10 (4.67%) persons. So, we contacted 204 ones (81 positive for hepatitis C, 117 for hepatitis B, and 6 for HIV). Among 204 reactive donors, 137(67.15%) were referred  out of whom 86 ones (42.15%) were referred after the first call. The response rate was more in educated ones. The response rate was not related to age, gender, and type of reactive tests. Among non-responded reactive donors, the major reasons were, not having enough time, travelling, and long distance.
 
Conclusions 
In this study, the response of reactive blood donors were 67.15%. For better response rate, having the  precise  donor  registry and  informing donors regarding the importance of blood safety and TTI are necessary.
 
 

M.p. Samiee, Dr. A. Chegini, Dr. M. Shahabi, Dr. A. Teimourpour,
Volume 21, Issue 1 (3-2024)
Abstract

Abstract
Background and Objectives
Regular blood donors may experience iron deficiency due to repeated blood donation. Genetic differences might have an impact on iron deficiency in regular blood donors. Some of these genes include those involved in activities related to iron absorption and transfer in blood. In this study, the association of the rs855791 single nucleotide polymorphism in TMPRSS6 gene with iron levels in male regular blood donors was investigated.

Materials and Methods
In this cross-sectional study, 130 male regular blood donors participated. CBC tests, serum iron, ferritin, and Total Iron Binding Capacity (TIBC) were performed on their blood samples. The genotypes of the target polymorphisms were determined using the allele-specific PCR method. All collected data were analyzed using R software for statistical analysis.

Results
The average age of the regular male blood donors was 45 years with a standard deviation of 10.5. Among the 130 regular blood donors, 28 individuals (21.54%) were homozygous for the T/T allele, 29 individuals (22.31%) were homozygous for the C/C allele, and 73 individuals were heterozygous for the C/T allele. No significant association was observed between the rs855791 single nucleotide polymorphism and iron assessment indicators.

Conclusions 
Single nucleotide polymorphism of TMPRSS6 gene (rs855791 v736A) was not associated with iron level and related quantities in regular blood donors.


 


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