Search published articles


Showing 2 results for Hemostasis
The efficacy of horse collagen(Antema) in hemostasis of bleeding due to dental procedures, pilonidal sinus surgery, hemorrhoidectomy and laminectomy
Mohebbi H.a, Abolghasemi H, Towliat Kashani S.m, Fanaii S.a, Kabir A,
Volume 3, Issue 3 (10-2006)
Abstract

  Abstract

 Background and Objectives

 Hemostasis and control of bleeding are important principles in surgery. Control of bleeding with normal procedures such as cauterization and ligation is sometimes hard and even impossible. Considering different effects of collagen including hemostasis acceleration, complete absorption, tissue repair, and flexibility and appropriate traction, it can help maintain hemostasis.

 

 Materials and Methods

 In a randomized controlled clinical trial, 92 cases and 91 controls were compared. Horse collagen (Antema) was used in cases while routine procedures were implemented in controls. Patients were evaluated in 4 groups involving dental procedures, pilonidal sinus open surgery, hemorrhoidectomy, and laminectomy. Statistical indices such as mean, standard error, and statistical tests such as t-test and chi-square were used in the analysis.

 

 Results

 Mean age was 29.48 ± 1.29 in the cases and 33.2 + 1.5 in the control group. Seventy four (36 cases, 38 controls) undergoing dental procedures, 61(31 cases, 30 controls) pilonidal sinus open surgeries, 31(18 cases, 18 controls) hemorrhoidectomies, and 12(7 cases, 5 control) laminectomies were investigated. Despite higher severity of bleeding in cases (p=0.011, r=0.247), the time of bleeding control (p<0.001) and the time of complete hemostasis(p<0.001) were lower in cases than in the control group.

 

 Conclusions

 Antema is effective in hemostasis and it may be used as an adjunct material in hemostasis.

  

 Key words : Collagen, Hemorrhage, Hemostasis, Surgery 


Comparison of the effect of natural silk and Chitohem powder on blood clotting time: an in vitro study
Dr. F. Owlia, Dr. M.h. Akhavan Karbasi, Dr. E. Babaei Zarch,
Volume 21, Issue 1 (3-2024)
Abstract
Abstract
Background and Objectives
Uncontrolled post-operative bleeding can lead to several problems and tissue repair disorder indentistry. This study has been conducted to compare the effect of Chitohem and natural silk on the onset of clot formations.

Materials and Methods
This laboratory study was carried out with a dependent parallel design. Three drops of blood were taken from each of 32 participants in the study. Fifty milligram Chitohem and natural silk powder were poured on two blood drops, respectively. The clot formation time was measured for all three groups simultaneously. Duration between pouring powder and starting of clot formation was recorded. Data analysis was performed using paired t-test and repeated measure ANOVA methods using SPSS 17 software.

Results
Participants composed of 20 (62.5%) women and 12 (37.5%) men. The average age of the participants was 43.33 ± 4.08 years. The average time periods of the onset of blood clot formation in Chitohem group, natural silk and control group were 90.97 ± 29.99, 141.97 ± 49.10, and 195.44 ± 58.70 second, respectively. Paired t-test showed the mean time of clot formation was significantly different among groups (p = 0.0001).

Conclusions 
Based on the obtained results, it seems that although effect of “organic natural silk” on coagulation time was less than “Chitohem”, but silk has an acceptable hemostatic effect. The simultaneous use of natural silk and Chitohem can have a synergistic effect.

 

Page 1 from 1     

© 2025 CC BY-NC 4.0 | Scientific Journal of Iran Blood Transfus Organ

Designed & Developed by : Yektaweb