Scientific Journal of

  Abstract

 Background and Objectives

 The aim of this research is to evaluate the effect of eight weeks of selected training on hematological indexes in women. Thirteen girls of Ray Branch of Azad University were selected non-randomly.

 Materials and Methods

 In this research, the effect of eight weeks of aerobic training including 40-minute running twice a week with 60% to 65% reserve heart rate on hematocrit, RBC, hemoglobin, blood indexes (MCH,MCV,MCHC), serum iron, transferrin concentration, serum ferritin and TIBC were examined. For data collection, blood samples before and after performance of the eight week training were obtained. The methods used were Sianoment colorimetric method to measure Hb, MCH, MCV, and MCHC, automatic machines to measure iron, and ferritin IRMA kit to measure ferritin concentration. Finally, the data were analyzed by t-student method.

 Results

 The results showed that eight weeks of aerobic training caused decrease in Hct, RBC, Hb, serum iron, transferring concentration and serum ferritin in girls (p< 0.05).

 Conclusions

 Aerobic training can place a reduction impact on some hematological indexes in women.�

 �

 Key words : Aerobic Exercise, Red Blood Cells, Transferrin, Ferritins

  Abstract

 Background and Objectives

 Exposure to infectious blood and body fluids increase risk of occupationally acquired HIV among nurses. Discrimination in care and treatment of AIDS patient is one of the challenging ethical issues in nursing. The aim of this study was to determine fear of being at risk of acquiring HIV, willingness to care, and discrimination in care and treatment of AIDS patients among nurses.

 Materials and Methods

 In this descriptive – cross sectional study, 165 nurses of internal and infectious wards from four selected hospitals of Tehran and Shahid Beheshti University of Medical Sciences participated. Data were collected by self-administered questionnaires. The instruments used included "demographic data form", "risk perception scale", "willingness to care for people living with HIV/AIDS"questionnaire, and "discrimination against AIDS" questionnaire. Data were analyzed by using SPSS 14, t-test, and pearson correlation.

 Results

 Out of 165 nurses, 36.4% had sever fear of being at risk of acquiring HIV, 81.8% were evaluated to be neutral in willingness to care of AIDS patients, and 54.5% agreed with moderately discrimination practice against AIDS patients. There was a significant correlation between fear of being at risk of acquiring HIV with discrimination in care and treatment of AIDS patients (p=0. 003) and willingness to care (p= 0.007).

 Conclusions

 It seems that education efforts about universal precautions, ethical issues, and patient rights should be made in order to reduce fear of being at risk of acquiring HIV, decrease discrimination in care and treatment of AIDS patients and increase willingness to care.

  Abstract

 Background and Objectives

 Blood transfusion is a modality of knowledge important for health care personnel to know about its different aspects. The aim of this study was to assess the knowledge of health care personnel in two hospitals of Zahedan about blood products, blood use, and adverse reactions.

 Materials and Methods

 In a study in two hospitals of Zahedan, 170 randomly selected employees from the hospital wards with the highest level of blood use participated. Data were collected via a questionnaire. For data analysis, SPSS, chi-square tests, t-test, ANOVA, and Pearson correlation coefficients were used.

 Results

 The average knowledge score of the personnel of Khatam Hospital was estimated to be 11.13 ± 3.68 and Ali ibn Abi Talib Hospital 13.31 ± 2.19. The average knowledge score of the two hospitals was 12.34 ± 3.13 with one hospital being significantly more knowledgeable than the other. But there was no correlation between age, gender, education, and work experience with the knowledge level (p > 0.01).

 Conclusions

 The results showed that the average knowledge score of health care personnel about blood transfusion is low at the two hospitals in Zahedan. Therefore, an academic course about blood transfusion should be dedicated to medical students in universities.

  Abstract

 Background and Objectives

 A common polymorphism at codon 72 in the p53 gene has been associated with the increased risk for lung, oral, prostate, breast and colorectal cancers. We studied this polymorphism in acute myeloid leukemia specimen from Alzahra Hospital in Isfahan city.

 Materials and Methods

 In the present case-control study, 59 whole blood specimen from normal people and 59 acutemyeloid leukemia specimen were analyzed. p53 codon 72 genotypes were identified using allele-specificPCR. Chi-square test was used for the comparison of the frequency distribution of three genotypes of codon 72 in cases and control specimen. 

 Results

 Resulting PCR products were either 177bp for proline allele or 141bp for arginine allele. The genotype distribution for p53 polymorphism showed 11.9%, 81.4%, and 6.8% for the Arg/Arg, Arg/Pro, and Pro/Pro genotypes in control samples and 33.9%, 61%, and 5.1% in acute myeloid leukemia specimen, respectively. The differences in the distribution of p53 codon 72 polymorphism between the cases and controls were statistically significant (p = 0.04).

 Conclusions

 Deferasirox is relatively more effective than deferoxamine in reducing iron content of the liver and heart. Moreover, deferasirox is more effective in reducing cardiac iron content relative to liver iron content.