Search published articles


Showing 2 results for Mohamadimaram

M.r. Mohamadimaram, Dr. A. Gharehbaghian, Dr. A.r. Baghestani, B. Vahidianfar, Dr. A.r. Abdollahi, E. Razani, M. Khansari,
Volume 16, Issue 2 (Summer 2019)
Abstract

Abstract
Background and Objectives
There are many antibodies and antigens that cause blood group related transfusion reactions. In this study we aim to find the prevalence of blood group antibodies in patients at different ages and with different gender.
 
Materials and Methods
In this descriptive study, we screened 30659 patients (59% female and 41% male, age range 1-85) referring to different wards of Imam Khomeini complex hospital during 2017-2018 for presence of any antibodies against blood group antigens. Then, for those patients with screened positive antibody we identified the antibody in each patient. Finally we categorized the antibody positive patients based on their main ABO and Rh blood group of all wards such as cancer, hematology, general and also separately for postpartum ward.
 
Results
Out of 30659 patients in all wards, 123 and  out of 4364 just in postpartum ward, 20 patients had positive antibody. The most prevalent alloantibodies were detected to be anti-E(31.7%), anti-K(30.8%), and anti-D(14.6%) in order.
 
Conclusions 
Anti-E and anti-K are the most likely antibodies presenting in patients with positive antibody screening results awareness of which can be helpful in storing blood components with rare blood groups. Moreover,  the evaluation of common alloantibodies in the postpartum ward shows that the administration of RhoGAM might not be adequate in HDFN prevention and other antibodies should be considered in this regard.
 
 

M.r. Mohamadimaram, Dr. A. Gharehbaghian, Dr. A.r. Abdollahi, M. Khansari,
Volume 17, Issue 2 (Summer 2020)
Abstract

Abstract
Background and Objectives
Blood transfusion related alloimmunization is common among patients receiving regular blood transfusion, especially thalassemia patients. In this study we aimed to find the prevalence of alloimmunization among patients of thalassemia.
 
Materials and Methods
In this desciptional study, we screened 305 thalassemia patients (53.8% female and  46.2% male, age 4-38) referring to Imam Khomeini Hospital during 2017-2018 for presence of antibodies against blood group antigens. Then for those patients of positive antibody screening result we identified the antibody in each patient.
 
Results
Seven out of 305 patients in this study had positive antibody screening results. The most prevalent alloantibodies were detected to be anti-K (6 patients, 85.7%) and anti-E (2 patients, 28.57%). Also, 2 out of 7 patients with positive antibody results presented dual antibody of anti-K and anti-E.
 
Conclusions 
According to the results, anti-K and anti-E are the most likely antibodies presenting in patients of thalassemia with positive antibody screening results. This point is important to bear in mind in providing special blood supplies for thalassemics who are in need of regular blood transfusion. Prior to treatment of multitransfused patients like thalassemia the phenotyping of patients for important blood groups of Kell and Rh should be considered.
 


Page 1 from 1     

© 2025 CC BY-NC 4.0 | Scientific Journal of Iran Blood Transfus Organ

Designed & Developed by : Yektaweb