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Sci J Iran Blood Transfus Organ 2015, 11(1): 87-92 Back to browse issues page
A case report of a patient with multiple warm and cold agglutinin with strong clinical importance
B. Ghezelbash, M. Moghaddam
Keywords: Key words: Blood Transfusion, Agglutination, cold agglutinins
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Type of Study: case report | Subject: Imunohematology
Published: 2014/03/16
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References:
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Case Report
 
 
 
 
Sci J Iran Blood Transfus Organ 2014; 11(1): 87-92
 
 
 

A case report of a patient with multiple warm and
cold agglutinin with strong clinical importance
 
Ghezelbash B.1,2, Moghaddam M.1
 
 
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Ardabil Regional Educational Blood Transfusion Center, Ardabil, Iran
 
 
 
 
Abstract
Background and Objectives
The unexpected alloantibodies are usually found in the sera of those patients who have a history of blood transfusion and pregnancy. These alloantibodies cause many complications in patients with post-transfusion delayed hemolytic transfusion reactions.
 
Case
A 24-year-old man with melana, blood vomiting, and the history of discopathy and consumption of moleksicam was observed. In laboratory tests, incompatibility of the cross-match test and discrepancy of blood grouping were observed. In the analysis of the antibody screening,  positive reactions were observed with all of the cells in different phases of panels 3 and 11. On the next visit, similar results were obtained after 6 months.
 
Conclusions 
If indicated for blood transfusion, only autologous blood is recommended to be administered to prevent hemolytic transfusion reactions.
 
Key words: Blood Transfusion, Agglutination, cold agglutinins
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Received: 17 Aug  213
Accepted: 7 Dec  2013
 
 
 
 

Correspondence: Ghezelbash B. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine and Ardabil Regional Educational Blood Transfusion Center.
Postal Code: 5613774111, Ardabil, Iran. Tel: (+98451) 3361408; Fax: (+98451) 3361409
                E-mail: behruzghezelbash@yahoo.com
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Ghezelbash B, Moghaddam M. A case report of a patient with multiple warm and cold agglutinin with strong clinical importance. Sci J Iran Blood Transfus Organ. 2015; 11 (1) :87-92
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Volume 11, Issue 1 (Spring 2014 2015) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
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