Volume 10, Issue 2 (Summer 2013)                   Sci J Iran Blood Transfus Organ 2013, 10(2): 140-146 | Back to browse issues page

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Chegini A, Mirrezaie S, Poorreza M, Rezaie A, Anbardan A. Assessment of plateletphersis donation in Tehran Blood Center . Sci J Iran Blood Transfus Organ 2013; 10 (2) :140-146
URL: http://bloodjournal.ir/article-1-767-en.html
Assessment of plateletphersis donation in Tehran Blood Center
A. Chegini * , S.M. Mirrezaie , M. Poorreza , A.R. Rezaie , A.J. Anbardan
Keywords: Key words : Plateletpheresis, side effects, Blood Donation
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Original Article
 
 
 
 
Sci J Iran Blood Transfus Organ 2013; 10(2): 140-146
 
 
 

Assessment of plateletphersis donation in Tehran
Blood Center
 
Chegini A.1,2, Mirrezaie M.1,2, Poorreza M.1,2, Rezaie A.R.1,2,  Anbardan A.J.1,2
 
 
 
1Blood Transfusion Research Center, High Institute for Research and Education on Transfusion Medicine, Tehran, Iran
2Tehran Regional Educational Blood Transfusion Center, Tehran, Iran
 
 
 
Abstract
Background and Objectives
Additional and more effective platelets can be gained through plateletphersis which at times equals platelets of 8 units of blood. Patients are exposed to a less number of donors through prescription of such platelets. Although side-effects of plateletphersis are low among donors but side-effects vary at different centers.  Illustration of plateletphersis production side-effects at Tehran Blood Bank is the aim.
 
Materials and Methods
This is a retrospective study on plateletphersis donors from 2005 to March 2011. Research was carried on 309 total blood donors who met Iran blood transfusion standards; CBC was carried out on all donors and those with Hb and platelet higher than 12.5 and 150.000 were entered into the study.  Information regarding aphersis sessions was compiled in donors’ forms including side-effects during platelet donation and they were classified as mild, intermediate  and severe according to definition.
 
Results
In the study, 302 cases of plateletphersis were carried out in which 81% of donors were male and 19% female; while the mean age of donors was 35.3 ± 9.8 .  The most occurring side-effects among donors were mild/medium vasovagal donation reaction 1.6% and citrate poisoning 1.6% of which 0.3% was of the intermediate type.
 
Conclusions 
Plateletphersis is safe and occurrence of side-effects is low.  Side-effects occur mostly among younger and first time donors.
 
Key words: Plateletpheresis, side effects, Blood Donation
 
 
 
 
 
Received: 7 Dec 2010
Accepted:9 Feb 2013
 

Correspondence: Chegini A., MD. Specialist in Anesthesiology. Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education on Transfusion Medicine and Tehran Regional Educational Blood
             Transfusion Center.
             P.O.Box: 14166-13141, Tehran, Iran. Tel: (+9821) 88963034; Fax: (+9821) 88959096
             E-mail: azita_chegini@yahoo.com
Type of Study: Research | Subject: Blood transfusion medicine
Published: 2013/08/24
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