Volume 19, Issue 1 (Spring 2022)                   Sci J Iran Blood Transfus Organ 2022, 19(1): 44-51 | Back to browse issues page

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Kasraian L, Afsar Z, Shirazi B, Farahangiz M, Naderi N. Evaluation of complications of ABO incompatibility following blood transfusion in 2019. Sci J Iran Blood Transfus Organ 2022; 19 (1) :44-51
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Sci J Iran Blood Transfus Organ 2022;19 (1): 44-51
Original Article
 


Evaluation of complications of ABO incompatibility
following blood transfusion in 2019

Kasraian L.1,2, Afsar Z.3, Shirazi B.3, Farahangiz M.3, Naderi N.3,4



1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Shiraz Blood Transfusion Center, Shiraz, Iran
3Shiraz University of Medical Sciences, Shiraz, Iran
4Shiraz Anesthesiology and Critical Care Research Center. Shiraz, Iran



Abstract
Background and Objectives
One of the dangers of blood transfusions is the mistakes that lead to the wrong blood transfusion to the patient. This study was performed to identify the types of errors that lead to incompatible transfusions to prevent their recurrence and increase recipients health.

Materials and Methods
This cross-sectional study was performed on complications of ABO incompatibility caused by transfusion in 2019 in Shiraz hospitals. Demographic characteristics of blood recipients (age, sex, diagnosis, history of transfusion, blood type), type of product received, blood type of product received, incompatible blood volume injected, symptoms and causes of ABO incompatibility were determined. Chi-square and t-test were used to analyze data.

Results
A total of 9 complications of ABO incompatibility were reported; 7 cases (77.8%) were due to packed red blood cells, one case (11.1%) due to platelet injection and one (11.1%) due to plasma injection. Seven cases occurred in patients undergoing surgery, one case in neonates and one in thalassemia patients. In terms of clinical symptoms, only one patient developed chills. The rest of the patients had no symptoms. The most common error leading to inconsistency was the lack of accurate identification in 6 cases (66.7%) and in 2 cases (22.2%) sampling error and in one (11.1%) incorrect group writing.

Conclusions 
It seems that in order to promote safe blood transfusion, it is important to investigate the occurrence of ABO incompatibilities in order to identify blood transfusion chain errors in order to identify the causes of errors and prevent the recurrence of these complications.

Key words: ABO Blood-Group System, Blood Transfusion, Complications




Received:  20 Sep 2021
Accepted: 24 Jan 2022


Correspondence: Naderi N. Assistant Professor of Anesthesiology and Critical Care of Shiraz Anesthesiology and Critical Care Research Center. Shiraz University of Medical Sciences.
Postal code: 7195864877, Shiraz, Iran. Tel: (+9871) 36287001; Fax: (+9871) 36264006
E-mail:
1- Acridine Orange
1- Biological safety cabinet
1- Platelet Concentrate
2- Food and Drug Administration
3- Normal Skin Flora
4- Platelet Rich Plasma-Platelet Concentrate
5- Eosin-Methylene blue
6- Thioglycolate
lnima_naderi54@yahoo.com

 
Type of Study: Research | Subject: Blood Transfusion
Published: 2022/03/30

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