[Home ] [Archive]   [ فارسی ]  
:: Main :: About us :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 19, Issue 1 (Spring 2022) ::
Sci J Iran Blood Transfus Organ 2022, 19(1): 61-74 Back to browse issues page
Plasma industry history at a glance
A. Aghaie
Abstract:   (554 Views)
Abstract
Background and Objectives
The plasma industry started during World War II with the need for Plasma Derived Medicinal Products (PDMP). About 30 major plasma products are now commercially available, the most important of which are albumin, coagulation factors and immunoglobulin. Demand for these products is still growing, and these products have become particularly important not only in the treatment of diseases but also in global trade. The article is a brief overview on the evolution of plasma industry over the past eighty years.

Materials and Methods
This review was done by searching for articles in Google Scholar, PubMed, Scopus databases, based on aspects of the evolution of the plasma industry, and the cost of producing plasma derivatives, from the beginning of this industry, from 1940 to 2021. Additionally, private sector entry and cost and benefit of viral deactivation processes in plasma industry was selected.

Results
The plasma industry has experienced tremendous progress over the years and faced many problems, and despite advances in biotechnology, this industry is a unique necessity in the health of human societies. The production of plasma-derived pharmaceutical products is a complex activity and involves several stages of operational units.

Conclusions 
There are many challenges and opportunities in the future of plasma industry. It seems that the emergence of new pathogens, the need for new PDMPs, and the potential to create new consumer markets, will be a challenge for plasma industry in the future. But the increasing demand can provide a good opportunity to change strategies and optimize consumption. The development of recombinant methods provides a good alternative to these products. In addition, the potential of using surplus plasma for local production provides an opportunity for developing countries.

 
Keywords: Plasma, Industry, Albumin
Full-Text [PDF 427 kb]   (172 Downloads) |   |   Full-Text (HTML)  (516 Views)  
Type of Study: Review Article | Subject: Blood Transfusion
Published: 2022/03/30
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Aghaie A. Plasma industry history at a glance. Sci J Iran Blood Transfus Organ. 2022; 19 (1) :61-74
URL: http://bloodjournal.ir/article-1-1410-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 19, Issue 1 (Spring 2022) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
Persian site map - English site map - Created in 0.04 seconds with 31 queries by YEKTAWEB 4419