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:: Volume 17, Issue 1 (Spring 2020) ::
Sci J Iran Blood Transfus Organ 2020, 17(1): 27-35 Back to browse issues page
Evaluation of Retrograde Autologous Priming (RAP) effect on Hemodilution and transfusion rate in operation room and ICU
F. Kargar Dr., B. Ghadrdoost Dr., N. Aghdaii Dr., A. Ghanbari
Keywords: Cardiac Surgery, Blood Transfusion, Hemodilution
Full-Text [PDF 408 kb]   (244 Downloads)     |   Abstract (HTML)  (1503 Views)
Type of Study: Research | Subject: Heart and Vessels Surgeon
Published: 2020/03/16
Full-Text:   (441 Views)
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Sci J Iran Blood Transfus Organ 2020;17(1): 27-35
Original Article
 

 

Evaluation of Retrograde Autologous Priming (RAP)
effect on Hemodilution and transfusion rate in operation
room and ICU
 
Kargar F.1, Ghadrdoost B.1, Aghdaii N.1, Ghanbari A.1
 
 
1Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
 
 
 
Abstract
Background and Objectives
To perform open heart surgery, the patient needs to be placed on the bypass system. This initial volume causes excessive dilution of the patient's blood and the use of blood products, which can alter the surgical procedure and recovery of the patient. The purpose of this study was to evaluate the usefulness of performing a retrograde autologous prime to reduce blood products consumption.
 
Materials and Methods
This is a prospective randomized clinical trial to evaluate whether RAP can reduce hemodilution in CPB and prevent allogeneic blood transfusion. In this study, 59 consecutive patients were randomly divided into two groups of RAP - with reverse autologous priming (n = 28) and control (Non RAP) - with normal priming (n = 31) being evaluated at Shahid Rajaee Cardiovascular Center between 1396-97.
 
Results
Statistical evaluations were performed with Chi Square, T-Test, and Mann-Whitney U tests. It was identified by placing patients on bypass, hemoglobin and hematocrit in the first and second samples, end of bypass, and on ICU that was significantly higher in the experimental group. The number of patients receiving the product and the number of products consumed in the control group were significantly higher. The duration of mechanical ventilation was significantly lower but the ICU stay was not significantly different.
 
Conclusions 
From these results, it can be concluded that the implementation of RAP retrograde autologous priming can effectively preserve hemoglobin and hematocrit of patients in acceptable range and reduce the use of blood products in patients undergoing bypass.
 
Key words: Cardiac Surgery, Blood Transfusion, Hemodilution
 
 
 
 
 
Received:  28 Jul   2019
Accepted: 24 Dec 2019
 
 

Correspondence: Ghanbari A., MS in Perfusion Technician. Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences.
P.O.Box: 15745-1341, Tehran, Iran. Tel: (+9821) 22042026; Fax: (+9821) 22042026
E-mail: a.mghanbari@yahoo.com
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Kargar F, Ghadrdoost B, Aghdaii N, Ghanbari A. Evaluation of Retrograde Autologous Priming (RAP) effect on Hemodilution and transfusion rate in operation room and ICU. Sci J Iran Blood Transfus Organ. 2020; 17 (1) :27-35
URL: http://bloodjournal.ir/article-1-1293-en.html


Volume 17, Issue 1 (Spring 2020) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
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