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:: Volume 17, Issue 1 (Spring 2020) ::
Sci J Iran Blood Transfus Organ 2020, 17(1): 20-26 Back to browse issues page
Comparing frequency of injecting drug use among accepted HCV infected blood donors in different regions of Iran
F. Ranjbar Kermani, K. Mousavi Hosseini, S. Amini Kafi-Abad, M. Maghsudlu, Z. Sharifi, M.A. Mansournia
Keywords: Blood Donors, Hepatitis C, Blood Safety, Donor Selection, Iran
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Type of Study: Research | Subject: Infectious disease
Published: 2020/03/16
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References:
 
 
  1. WHO. Hepatitis C Fact Sheet. update July 2019. Geneva: World Health Organization. https://www.who.int/news-room/fact-sheets/detail/hepatitis-c; 2019.
  2. European Association for the Study of the Liver. EASL Recommendations on Treatment of Hepatitis C 2016. J Hepatol 2017; 66(1): 153-94.
  3. WHO. Global status report on blood safety and availability 2016. Geneva: World Health Organization; 2017.
  4. Khodabandehloo M, Roshani D, Sayehmiri K. Prevalence and trend of hepatitis C virus infection among blood donors in Iran: A systematic review and meta-analysis. J Res Med Sci 2013; 18(8): 674-82.
  5. Rezaei N, Amini-Kafiabad S, Maghsudlu M, Abolghasemi H. Risk factor analysis of hepatitis C virus seropositivity in Iranian blood donors: a case-control study. Transfusion 2016; 56(7): 1891-8.
  6. Huang Y, Guo N, Yu Q, Lv Y, Ma H, Yun Z, et al. Risk factors for hepatitis B and C infection among blood donors in five Chinese blood centers. Transfusion 2015; 55(2): 388-94.
  7. O’Brien SF, Xi G, Fan W, Yi QL, Osmond L, Delage G, et al. Are donors in Canada compliant with deferral for tattoos and piercing? Blood Transfus 2014; 12(1): 141-2.
  8. Custer B, Kessler D, Vahidnia F, Leparc G, Krysztof DE, Shaz B, et al. Risk factors for retrovirus and hepatitis virus infections in accepted blood donors. Transfusion 2015; 55(5): 1098-107.
  9. Mitrovic N, Delic D, Markovic-Denic L, Jovicic M, Popovic N, Bojovic K, et al. Seroprevalence and risk factors for hepatitis C virus infection among blood donors in Serbia: a multicentre study. Dig Liver Dis 2015; 47(7): 572-6.
  10. Alavian SM, Hajarizadeh B, Lankarani KB, Sharafi H, Daryani NE, Merat S, et al. Recommendations for the clinical management of hepatitis C in Iran: a consensus-based national guideline. Hepat Mon 2016; 16(8): e40959.
  11. Kermani FR, Hosseini KM, Kafi-abad SA, Maghsudlu M, Sharifi Z, Mansournia MA, et al. Update on Transmission Modes of Hepatitis C Virus Among Volunteer Iranian Blood Donors: Analysis of a Matched Case-Control Study by Penalized Conditional Logistic Regression. Hepat Mon 2018; 18(10): e69395.
  12. WHO. Blood donor selection: Guidelines on assessing donor suitability for blood donation. Geneva: World Health Organization; 2012.
  13. O'Brien SF, Fan W, Xi G, Yi QL, Goldman M, Fearon MA, et al. Declining hepatitis C rates in first-time blood donors: insight from surveillance and case-control risk factor studies. Transfusion 2008; 48(5): 902-9.
  14. He Y, Zhang J, Zhong L, Chen X, Liu HM, Wan LK, et al. Prevalence of and risk factors for hepatitis C
    virus infection among blood donors in Chengdu, China. J Med Virol 2011; 83(4): 616-21.
  15. Tanwandee T, Piratvisuth T, Phornphutkul K, Mairiang P, Permpikul P, Poovorawan Y. Risk factors of hepatitis C virus infection in blood donors in Thailand: a multicenter case-control study. J Med Assoc Thai 2006; 89(Suppl 5): s79-83.
  16. Murphy EL, Bryzman SM, Glynn SA, Ameti DI, Thomson RA, Williams AE, et al. Risk factors for hepatitis C virus infection in United States blood donors. Hepatology 2000; 31(3): 756-62.
  17. Ruta S, Cernescu C. Injecting drug use: A vector for the introduction of new hepatitis C virus genotypes. World J Gastroenterol 2015; 21(38): 10811-23.
  18. Degenhardt L, Peacock A, Colledge S, Leung J, Grebely J, Vickerman P, et al. Global prevalence of injecting drug use and sociodemographic characteristics and prevalence of HIV, HBV, and HCV in people who inject drugs: a multistage systematic review. Lancet Glob Health 2017; 5(12): e1192-1207.
  19. Bagheri Amiri F, Mostafavi E, Mirzazadeh A. HIV, HBV and HCV coinfection prevalence in Iran-a systematic review and meta-analysis. PloS One 2016; 11(3): e0151946.
  20. Sharhani A, Mehrabi Y, Noroozi A, Nasirian M, Higgs P, Hajebi A, et al. Hepatitis C Virus Seroprevalence and Associated Risk Factors Among Male Drug Injectors in Kermanshah, Iran. Hepat Mon 2017; 11(3): e0151946.
  21. Razjou F, Maghsudlu M, Nasizadeh S, Zadsar M. The impact of donor selection on blood safety in Iran. Transfus Apher Sci 2012; 47(1): 13-6.
 
 
 
 
 
 
 


 
 
 
Sci J Iran Blood Transfus Organ 2020;17(1): 20-26
Original Article
 

 

Comparing frequency of injecting drug use among accepted HCV infected blood donors in different regions of Iran
 
Ranjbar Kermani F.1, Mousavi Hosseini K.1, Amini Kafi-Abad S.1, Maghsudlu M.1, Sharifi Z.1,
Mansournia M.A.2
 
 
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2School of public Health, Tehran University of Medical Sciences
 
 
 
Abstract
Background and Objectives
Considering the importance of donor selection process in blood safety, this study aimed at comparison of frequency of intravenous drug use (IDU) among accepted HCV positive blood donors in different regions of Iran.
 
Materials and Methods
This cross sectional-analytical study was conducted on  serologically confirmed HCV positive blood donors who referred to blood transfusion centers for counseling all over the country during November 2015 to May 2017. All provinces were classified in three regions. IDU status and demographic specification of participants were analyzed using questionnaires. Chi square, fisher exact and ANOVA with STATA software version 13 were used for statistical analysis.
 
Results
Participants, according to the number of provinces, sample size and geographical proximity to three areas were classified including  76 from North; 105 from West-South and 90 from East- Center individuals with the mean ages of 37.73 ±  8.27, 38.83 ± 8.80 and 36.86 ± 8.63 and  history of IDU of 37 (48.68%), 45 (42.86%) and 41 (45.56%), respectively. No significant differences between different regions of the country were found in the frequency of IDU voluntary blood donors with hepatitis C, age, gender, education status, marriage status (p > 0.05).
 
Conclusions 
Approximately half of the voluntary blood donors with hepatitis C were IDUs. The frequency of IDU was similar among donors from different regions of Iran. Considering the fact that studied donors were found eligible in donor selection and donated the blood, though rejected during the screening phase, conducting research on the issue can increase the quality of blood donor selection and blood safety.
 
Key words: Blood Donors, Hepatitis C, Blood Safety, Donor Selection, Iran
 
 
 
Received: 24 Aug 2019
Accepted:  2 Dec 2019
 
 

Correspondence: Mousavi Hosseini K., PhD in Medicinal Chemistry. Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 82052160; Fax: (+9821) 88601599
E-mail: mkmousavi@yahoo.com
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Ranjbar Kermani F, Mousavi Hosseini K, Amini Kafi-Abad S, Maghsudlu M, Sharifi Z, Mansournia M. Comparing frequency of injecting drug use among accepted HCV infected blood donors in different regions of Iran. Sci J Iran Blood Transfus Organ. 2020; 17 (1) :20-26
URL: http://bloodjournal.ir/article-1-1287-en.html


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Volume 17, Issue 1 (Spring 2020) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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