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:: Volume 18, Issue 3 (Autumn 2021) ::
Sci J Iran Blood Transfus Organ 2021, 18(3): 171-179 Back to browse issues page
Evaluation of post- donation blood cell changes in donors undergoing plateletpheresis by Haemonetics MCS+
P. Fani, A. Chegini , M. Shaiegan, Sh. Samiee, E. Hajati
Keywords: Plateletpheresis, Blood Donors, Blood Cell Count, Platelet Count, Leukocyte Count, Erythrocyte Count
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Type of Study: Research | Subject: Blood donation
Published: 2021/10/2
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Sci J Iran Blood Transfus Organ 2021;18 (3): 171-179
Original Article
 
Evaluation of post- donation blood cell changes in donors undergoing plateletpheresis by Haemonetics MCS+ 
 
Fani P.1, Chegini A.1, Shaiegan M.1, Samiee Sh.1, Hajati E.1
 
 
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
 
 
 
Abstract
Background and Objectives
Apheresis is an efficient method for collecting blood products such as plasma, platelets, red and white blood cells. Considering the importance of donor health and due to the limited number of apheresis donors' health related articles, we decided to investigate the effect of apheresis on platelet count, hemoglobin, hematocrit levels, and total leukocyte counts of donors.
 
Materials and Methods
A descriptive cross-sectional study was performed on 25 donors who were eligible for inclusion criteria in the study from May 2016 to January 2017. Samples were taken from donors before and after platelet apheresis and also 7 days after platelet apheresis to be tested on blood cells. CBC samples were analyzed with calibrated Mindray BC 300 cell counter device and then results were recorded in the prepared checklist and analyzed by SPSS 23 software.
 
Results
Twenty five male donors had a mean age of  32.4 ± 9.97 years, minimum age 19 and maximum 59 and average weight 85.84 ± 17.2  kg, and mean height  178.2 ± 6.69. There was no significant change in WBC, RBC, HCT, and Hb before and after apheresis and 7 days later in Haemonetics MCS+. Platelet counts decreased immediately after donation from 235.720 ± 52.109  to 176.400 ± 44.240  (103/μL) and it reached to the level of before donation after 7 days (243.400 ± 67.399)(103 /μL).
 
Conclusions 
There was no significant change in WBC, RBC, HCT, and Hb before and 7 days after donation.
 
Key words: Plateletpheresis, Blood Donors, Blood Cell Count, Platelet Count, Leukocyte Count, Erythrocyte Count
 
 
 
 
 
 
Received:    9 Feb 2021
Accepted: 23 Jun 2021
 
 

Correspondence: Chegini A., MD. Specialist in Anesthesiology. Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 82052256; Fax: (+9821) 88601599
E-mail: a.chegini@ibto.ir
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Fani P, Chegini A, Shaiegan M, Samiee S, Hajati E. Evaluation of post- donation blood cell changes in donors undergoing plateletpheresis by Haemonetics MCS+. Sci J Iran Blood Transfus Organ. 2021; 18 (3) :171-179
URL: http://bloodjournal.ir/article-1-1239-en.html


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Volume 18, Issue 3 (Autumn 2021) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
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