Volume 17, Issue 4 (Winter 2020)
Sci J Iran Blood Transfus Organ 2020, 17(4): 315-321 |
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Niazi V, Shahbazi M. A case report of temporary and acquired vitamin K-dependent clotting factor deficiency without any response to administrated vitamin K. Sci J Iran Blood Transfus Organ 2020; 17 (4) :315-321
URL: http://bloodjournal.ir/article-1-1337-en.html
URL: http://bloodjournal.ir/article-1-1337-en.html
Abstract: (2113 Views)
Abstract
Background and Objectives
Vitamin K-dependent clotting factor deficiency (VKCFD) is usually an acquired problem due to liver disease, malabsorption, and overdose of warfarin. In the present paper the significance and role of vitamin K-dependent coagulation factors in menorrhagia were evaluated.
Case
We present a rare case of 43 year woman with acquired vitamin K deficiency and severe menorrhagia without any gynecological problem. The level of all Vitamin-K dependent coagulation factors, Fctor II, Factor VII, Factor IX, and Factor X decreased. Furthermore, even after multiple administration of Vitamin K and its oral consumption, still the level of coagulation factors and menorrhagia did not ameliorate.
Conclusions
Acquired VKCFD is one of the rare situations that can be life-threatening.
Background and Objectives
Vitamin K-dependent clotting factor deficiency (VKCFD) is usually an acquired problem due to liver disease, malabsorption, and overdose of warfarin. In the present paper the significance and role of vitamin K-dependent coagulation factors in menorrhagia were evaluated.
Case
We present a rare case of 43 year woman with acquired vitamin K deficiency and severe menorrhagia without any gynecological problem. The level of all Vitamin-K dependent coagulation factors, Fctor II, Factor VII, Factor IX, and Factor X decreased. Furthermore, even after multiple administration of Vitamin K and its oral consumption, still the level of coagulation factors and menorrhagia did not ameliorate.
Conclusions
Acquired VKCFD is one of the rare situations that can be life-threatening.
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