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A report of a Bombay phenotype case (Oh) during establishment of haemovigilance system in Bandar Abbas
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F. Jalali Farahani   , E. Charsizadeh , Z. Mozaffari Khorgoo , M. Moghaddam , R. Radmehr , M. Faranoush , M.R. Balali , N. Moradi Shamami , H. Ramezani , E. Shahebrahimi , M. Naderi Beni |
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| Keywords: Key words: Blood Transfusion, Iran, Hemovigilance, Agglutination |
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Type of Study: case report |
Subject:
Blood transfusion medicine
Published: 2013/12/21
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Full-Text: (4717 Views) |
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Sci J Iran Blood Transfus Organ 2014; 10(4): 406-410
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A report of a Bombay phenotype case (Oh) during
establishment of haemovigilance system in Bandar Abbas
Jalali Farahani F.1, Charsizadeh E.2, Mozaffari Khorgoo Z.2, Moghaddam M.1, Radmehr R.2,
Faranoush M.1, Balali M.R.1, Moradi Shamami N.1, Ramezani H.1, Shahebrahimi E.1, Naderi Beni M.1
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Bandar Abbas Regional Blood Transfusion Center, Bandar Abbas, Iran
Abstract
Background and Objectives
For people with Bombay phenotype due to the expression of strong IgM Anti H in their sera, transfusion with ABO group O blood will cause acute hemolytic reactions. Therefore, it is important to detect them.
Case
Following O blood type transfusion to a blood group O Rh positive patient with multiple trauma, acute hemolytic transfusion reaction happened. The reaction was recognized by the trained nurse in the haemovigilance system. In serologic studies, a high level of anti-H, anti-A, and anti-B was detected in the patient blood.
Conclusions
This case increased the number of Bombay phenotypes in Iran to 16. Therefore, using antibody screening test and existence of trained nurses and physicians with haemovigilance system in order exact management of transfusion reactions should be considered necessary.
Key words: Blood Transfusion, Iran, Hemovigilance, Agglutination
Received: 15 Oct 2012
Accepted:10 Mar 2013
Correspondence: Jalali Farahani F., Pathologist. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 82052217; Fax: (+9821) 88068748
E-mail: dr_fjalali@yahoo.com
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Jalali Farahani F, Charsizadeh E, Mozaffari Khorgoo Z, Moghaddam M, Radmehr R, Faranoush M, et al . A report of a Bombay phenotype case (Oh) during establishment of haemovigilance system in Bandar Abbas. Sci J Iran Blood Transfus Organ 2014; 10 (4) :406-410 URL: http://bloodjournal.ir/article-1-832-en.html
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