Mesenchymal stem cell biology, application and its role in regenerative medicine
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A. Dehghani Fard , N. Saki , M. Ahmadvand , M. Mahmoodinia Maymand , M. Mosahebi Mohammadi , M. Soleimani ![](./files/0allsites/images/pubmed20.png) |
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Abstract: (21668 Views) |
Abstract Background and Objectives Mesenchymal Stem Cells have extensive potential to proliferate and differentiate into different cell lineages. Their differentiation capability in vivo and in vitro makes them ideal tools for tissue engineering and regenerative medicine. Materials and Methods In the present study more than 100 recent published articles which are about isolation, culture and differentiation of MSCs were reviewed for application of MSC in regenerative medicine and tissue engineering. Results Clinical applications of MSCs seem to be in two distinctive lines: bio-scaffold design without immunological responses as well as multipotent stem cell without clinical obstacles. Conclusions MSCs due to their capacity of self-renewability, multilineage differentiation and immune modulatory effects are of great therapeutic potential for cell and gene therapy of congenital and degenerative disorders. |
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Keywords: Mesenchymal Stem Cells, Medicine, Tissue Engineering |
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Full-Text [PDF 361 kb]
(3014 Downloads)
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Type of Study: Review Article |
Subject:
Stem cells Published: 2013/08/28
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