fa COVID-19 و انتقال خون بيماري هاي عفوني Infectious disease مروري Review Article <div style="text-align: justify;"><span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="font-weight:bold"><span lang="FA" style="line-height:80%"><span style="font-family:Jadid"><span style="font-weight:normal">چکید</span></span></span><span lang="AR-SA" style="line-height:80%"><span style="font-family:Jadid"><span style="font-weight:normal">ه</span></span></span><span lang="FA" style="line-height:80%"><span style="font-family:Jadid"><span style="font-weight:normal"></span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i><span lang="FA" style="font-size:9.0pt"><span style="line-height:80%"><span style="font-family:Titr">سابقه و هدف </span></span></span></i></b></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:">بیماری کرونا ویروس که توسط </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">SARS-COV-2</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ایجاد می‌شود، در مدت کوتاهی اغلب نقاط دنیا را درگیر کرد.</span></span></span></b><b> </b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:">در زمان ظهور پاندمی به این گستردگی، بانک خون‌ها نیز تحت تاثیر قرار می‌گیرند. به دلیل شیوع گسترده </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">SARS-COV-2</span></span></b><b><span style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> دستورالعمل‌های جدیدی در مراکز انتقال خون اتخاذ گردیده است. بررسی اثرات پاندمی </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">SARS-COV-2</span></span></b><b><span style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> بر مراکز انتقال خون، اهدا و سلامت خون&nbsp; و استفاده از فرآورده های خونی برای درمان آن از اهداف این مقاله بود.</span></span></span></b></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i><span lang="FA" style="font-size:9.0pt"><span style="line-height:80%"><span style="font-family:Titr">مواد و روش‌ها</span></span></span></i></b></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:">در این مطالعه مروری، واژگان کلیدی در پایگاه‌های </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Science Direct</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">PubMed</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Scopus</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> و ژورنال‌های </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Science Nature</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Elsevier</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Cell</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">BMJ</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Blood</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> ، </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Transfusion</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> و </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">Lancet</span></span></b><b><span style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> جستجو شده و نهایتاً ۹۹ مقاله استفاده گردید.</span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%"></span></span></b></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i><span lang="FA" style="font-size:9.0pt"><span style="line-height:80%"><span style="font-family:Titr">یافته‌ها</span></span></span></i></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:">بیماری </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">COVID-19</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> اثرات منفی بر اهدا و سرویس‌های انتقال خون داشته است. از مسائل مهم این است که انگیزه اهداکنندگان با وجود پاندمی حفظ شود و مراکز درمانی با کمبود فرآورده‌های خونی روبه رو نشوند. </span></span></span></b><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">SARS-COV-2</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> چالش‌هایی در جذب اهداکنندگان و سلامت خون ایجاد کرده زیرا عفونت می‌تواند بدون علامت باشد. با این وجود، تا به امروز موردی از انتقال ویروس به واسطه تزریق فرآورده‌های خونی گزارش نشده است.</span></span></span></b></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i><span lang="FA" style="font-size:9.0pt"><span style="line-height:80%"><span style="font-family:Titr">نتیجه گیری</span></span></span></i></b></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:inter-ideograph"><span style="line-height:80%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span dir="LTR" style="font-size:9.0pt"><span style="line-height:80%">COVID-19</span></span></b><b><span lang="FA" style="font-size:11.0pt"><span style="line-height:80%"><span b="" badr="" style="font-family:"> اثرات منفی بر اهدا و ذخایر خون داشته است. مراکز خون سیاست‌های جدیدی را برای محافظت از اهداکنندگان و تأمین خون ایجاد کرده‌اند؛ از جمله اضافه کردن پرسش‌های جدید به پرسشنامه غربالگری اهداکنندگان و معافیت‌های جدید برای ابتلا، واکسیناسیون و مدیریت خون بیماران. پلاسمای هیپرایمیون، اگر چه به عنوان یک درمان احتمالی مطرح می‌شود، با این حال در این زمینه تناقضاتی وجود دارد.</span></span></span></b></span></span></span></span></span></span><br> <br> &nbsp;</div> <div dir="rtl" style="text-align: left;"><span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:12.0pt">Abstract</span></b><b><span style="font-size:12.0pt"></span></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i>Background and Objectives</i></b></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black">Coronavirus disease 2019 (COVID-19) which is caused by SARS-COV-2 has affected most parts of the world in a short period. Transfusion services are also affected during the emergence of a pandemic of this magnitude. Due to the widespread outbreak of SARS-COV-2, new guidelines have been adopted in blood transfusion centers. <a name="_Hlk124066427">Considering the impact of the SARS-COV-2 pandemic on blood transfusion services, blood donation, blood safety, and the use of blood products as a treatment for COVID-19 are addressed in this article</a>.</span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i></i></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i>Materials and Methods</i></b><b><i><span lang="AR-SA" dir="RTL" style="font-family:"Traditional Arabic""></span></i></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black">In this review, keywords were searched in Science Direct, PubMed, and Scopus databases, and the sites of Nature Science, Elsevier, Cell, BMJ, Blood, Transfusion, and Lancet journals, and finally 99 articles were used.</span></span></span></span></span></span><br> <br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i>Results</i></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black">In this article, in addition to a brief review of patient blood management, blood safety, and donor safety during the COVID-19 pandemic, the use of blood products as a treatment is considered.</span></span></span></span></span></span><br> <br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><i>Conclusions&nbsp; </i></b></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black">Hospitals and blood centers have created new policies and guidelines to protect donors and blood supplies including adding new questions to the donor questionnaire and adopting new deferrals for COVID-19 infection and vaccination. Although hyperimmune plasma (convalescent plasma) is proposed as a possible treatment, there are some contradictions in this field.</span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></span></span></span><br> <br> &nbsp;</div> COVID-19 , ترانسفیوژن, پلاسما, SARS-COV-2 COVID-19, Transfusion, Plasma, SARS-COV-2 66 80 http://bloodjournal.ir/browse.php?a_code=A-10-1491-2&slc_lang=fa&sid=1 N. Kazemi Babaahmadi نیلوفر کاظمی بابا احمدی 9100319475328460023369 9100319475328460023369 No مرکز تحقیقات انتقال خون ـ مؤسسه عالی آموزشی و پژوهشی طب انتقال خون M. Kheirandish مریم خیراندیش m.kheirandisah@ibto.ir 9100319475328460023370 9100319475328460023370 Yes دانشیار مرکز تحقیقات انتقال خون ـ مؤسسه عالی آموزشی و پژوهشی طب انتقال خون