Sachdev S, Dhawan HK, Khetan D, Marwaha N, Jain A, Sharma RR. White particulate matter in a packed red blood cells unit. Asian J Transfus Sci 2011; 5(2): 175-6.
Rentas FJ, Macdonald VW, Rothwell SW, McFaul SJ, Asher LV, Kennedy AM, et al. White particulate matter found in blood collection bags consist of platelets and leukocytes. Transfusion 2004; 44(7): 959-66.
Bang SU, Lee SM, Oh SC, Chung K, Lee. DJ. Macroaggregates in the packed red blood cell unit
during transfusion. Korean J Anesthesiol 2013; 65(6): 587-8.
Ram Kakaiya. Whole Blood Collection and Component Processing. In: Roback JD. Technical Manual. 17th ed. USA: AABB; 2011. p. 202
Truter EJ, Rossouw JJ, Böhm L. Studies on the ultrastructure of blood cells and the microaggregate fraction in stored human blood. Intensive Care Med 1981; 7(3): 115-9.
Iwamoto M, Curns AT, Blake PA, Jernigan DB, Holman RC, Lance-Parker SE, et al. Rapid evaluation of risk of white particulate matter in blood components by a statewide survey of transfusion reactions. Transfusion 2004; 44(7): 967-72.
Case Report
Sci J Iran Blood Transfus Organ 2015; 12(2): 179-182
A case report of a whole blood unit with white particulate matter
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
Abstract Background and Objectives
The accumulation of white particulate matter in blood bags, with the mechanism of formation unknown, has been rarely reported. However, the high number of platelets, blood lipids, and the like could help the white matter form.
Case
A 450 mL blood bag coated with 63 mL CPDA1 including the white matter detected was transferred from the blood center to the central quality control department. All test results on RBCs, white cells, platelets, hemoglobin, hematocrite, protein sera, triglyceride, and cholestrol were negative. The donor had no record of any medicine consumption. The microbial culture of white matter was negative.
Conclusions
Although no correlation has been clearly found between the accumulation of white matter and transfusion reactions, it is recommended to prevent administering the white matter including blood bags to the patient; these blood bags should be quarantined for further analysis. The appearance of the blood bags before transfusion should be checked.
Correspondence: Amini Kafi-Abad S, MD. Pathologist. Associate Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 88601558; Fax: (+9821) 88601542
E-mail: s.amini@ibto.ir
Namiranian P, Tirandazi B, Soleimani Frizhand A, Hosein Beigi S, Amini-Kafi Abad S. A case report of a whole blood unit with white particulate matter. Sci J Iran Blood Transfus Organ 2015; 12 (2) :179-182 URL: http://bloodjournal.ir/article-1-866-en.html