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The comparison of the prevalence rates of HBV, HCV, and HIV in blood donors having deferred for high risk behaviors
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M. Samadi   , A.H. Ghasemzade , Gh. Sarizade , S. Ebrahimi , Sh. Saati , A. Abassinejad-Pour , L. Nazar Ardekani |
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| Keywords: Key words: Blood Donors, Hepatitis B, High-Risk Sex, HIV |
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Type of Study: Research |
Subject:
Infectious disease
Published: 2013/12/18
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Full-Text: (1103 Views) |
References:
- Ankra-Badu GA, Ahmad M, Sowayan S, Bashawri L. Demographic characteristics of seropositive donors in Al-Khobar. Ann Saudi Med 2001; 21(1-2): 113-6.
- Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ. The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study. N Engl J Med 1996; 334(26): 1685-90.
- Lackritz EM, Satten GA, Aberle-Grasse J, Dodd RY, Raimondi VP, Janssen RS, et al. Estimated risk of transmission of the human immunodeficiency virus by screened blood in the United States. N Engl J Med 1995; 333(26): 1721-5.
- Kleinman S, Busch MP, Korelitz JJ, Schreiber GB. The incidence/window period model and its use to assess the risk of transfusion-transmitted human immunodeficiency virus and hepatitis C virus infection. Transfus Med Rev 1997; 11(3): 155-72.
- Abolghasemi H, Kheirkhah M, Hosseini SM. Survey of the reasons for the deferral of blood donors in Tehran Blood Transfusion Center. Hakim 2002; 5(2): 119-25. [Article in Farsi]
- Ebrahamian Z, Fazilati M, Akbari N, Hariri MM, Fatehifar MR. Correlation of deferral rate with the frequency rate of viral markers of HBV, HCV and HIV in blood supplies during 2004 to 2009. Sci J Iran Blood
Transfus Organ 2011; 8(2): 130-6. [Article in Farsi]
- Esmaeili H, Hajiani Gh, Esmaeili M, Mankhian AR, Aziz-Zadeh M, Hamidian Z. Study of infection with hepatitis B, C, HIV and syphilis blood donors in Bushehr at 2002. Iranian Journal of Infectious Diseases 2004; 12(36): 85-8. [Article in Farsi]
- Mwangi JW. Viral markers in a blood donor population. East Afr Med J 1999; 76(1): 35-7.
- Yektaparast B, Alavian SM, Kabir A, Vahid T, Kafaee J, Gharehbaghian A. Hepatitis B prevalence and risk factors in blood donors in Ghazvine , Iran. Vox Sang 2004; 87(Suppl 3): P24.
- Amini Kafiabadi S, Talebian A, Amoo-Hossein B, Rammau S. The prevalence of hepatitis B markers in volunteer blood donors in different regions in Iran. Vox Sang 2004; 87(Suppl 3): P101.
- Alavian SM, Gholami B, Masarrat S. Hepatitis C risk factors in Iranian volunteer blood donors: a case-control study. J Gastroenterol Hepatol 2002; 17(10): 1092-7.
- Kasraian L, Torab Jahromi SA. Prevalence of major transfusion viral infections HCV, HBV and HIV in Shiraz blood donor from 2000-2005. Sci J Iran Blood Transfus Organ 2007; 3(5): 373-8. [Article in Farsi]
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Sci J Iran Blood Transfus Organ 2014; 10(4): 347-352
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The comparison of the prevalence rates of HBV, HCV,
and HIV in blood donors having deferred
for high risk behaviors
Samadi M.1,2, Ghasemzade A.H.1,2, Sarizade Gh.1,2, Ebrahimi S.1,2, Saati Sh.1,2,
Abassinejad-Pour A.1,2, Nazari Ardekani L.1,2
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Khuzestan Regional Educational Blood Transfusion Center, Ahwaz, Iran
Abstract
Background and Objectives
Selection of healthy blood donors is an important process to identify high risk volunteers. Monitoring and evaluation of the deferral procedure is of the highest importance to balance blood availability and safety. The aim of the current study was to compare the prevalence of HBV, HCV and HIV serologic markers between deferred donors and eligible blood donors to assess the value of the current donor selection process.
Materials and Methods
Six hundred and nineteen voluntary blood donors in Ahwaz city were included. Serum samples from deferred and eligible donors were examined for serologic markers of HBV, HCV, and HIV using enzyme-linked immunosorbent assay. All positive samples were confirmed using confirmatory tests.
Results
The prevalence rates of HBV infection among deferred and eligible blood donors were estimated to be 0.5% and 0.2%, respectively. Anti-HCV reactivity was detected among 1.3% of deferred blood donors. Moreover, the prevalence of anti-HIV among deferred and eligible blood donors was 0.2% and 0.05%, respectively. We found that the overall prevalence rates of HBsAg, anti-HCV, and anti-HIV in the deferred blood donors are significantly higher than those in the eligible blood donors.
Conclusions
The results of this study indicate the high prevalence rate of blood borne infections. Moreover, it seems that the current donor selection process is effective to identify healthy blood donors. However, the effectiveness of some of the currently used deferral questions in reducing viral risks warrants further study.
Key words: Blood Donors, Hepatitis B, High-Risk Sex, HIV
Received: 4 Nov 2012
Accepted:14 May 2013
Correspondence: Samadi M., MD. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine and Khuzestan Regional Educational Blood Transfusion Center.
Postal Code: 613363371, Ahwaz, Iran. Tel: (+98611) 2262742; Fax: (+98611) 2262740
E-mail: samadidr@yahoo.com
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Samadi M, Ghasemzade A, Sarizade G, Ebrahimi S, Saati S, Abassinejad-Pour A et al . The comparison of the prevalence rates of HBV, HCV, and HIV in blood donors having deferred for high risk behaviors . Sci J Iran Blood Transfus Organ 2014; 10 (4) :347-352 URL: http://bloodjournal.ir/article-1-826-en.html
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