:: Volume 18, Issue 2 (Summer 2021) ::
Sci J Iran Blood Transfus Organ 2021, 18(2): 71-78 Back to browse issues page
Evaluation and analysis of quality control results of Fresh Frozen Plasma units in Iranian blood transfusion centers during 1397-1398
M. Abedini, Z. Motamedi, A. Soleimany Ferizhandy, S. Amini Kafi-Abad
Abstract:   (487 Views)
Abstract
Background and Objectives
Fresh frozen plasma is the plasma that retains its unstable protein activity during the freezing process. The purpose of this study was to investigate the quality of FFP products during 1397- 1398.
 
Materials and Methods
In this cross-sectional descriptive study, quality control results of FFP parameters of blood transfusion departments were collected in EXCEL 2019. The ratio of compliance was investigated using Med Calc Statistical Software and chi squared statistical method. Values of mean ± 1SD, parameters volume, FVIII, WBC, RBC and platelet counts and protein levels were compared by T-test method.
 
Results
In the year 1397, 18744 and in the year 1398, 18282 FFP units were evaluated in terms of quality. The percentage of compliance of FFP quality parameters was increased in 1398 compared to 1397. The differences in the percentage of compliance in FVIII, RBC count and protein parameters were significant (p ≤ 0.05). Mean FVIII increased significantly and the number of  RBC, WBC, and platelets of FFP products in 1398 was significantly decreased compared to 1397 (p ≤ 0.05).
 
Conclusions 
This study showed that more than 99% of the FFP units evaluated during the years 1397-1398 were in accordance with the standards of the Iranian Blood Transfusion Organization. Also, increase in the percentage of compliance with qualitative parameters in 1398, the increase in the average FVIII activity, and the significant decrease in the number of RBC, WBC and platelets of FFP products in 1398 compared to 1397 were indicative of improvement in the production process.
Keywords: Fresh Frozen Plasma, WBC, RBC
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Type of Study: Research | Subject: Blood Transfusion
Published: 2021/07/1


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Volume 18, Issue 2 (Summer 2021) Back to browse issues page