:: Volume 17, Issue 4 (Winter 2020) ::
Sci J Iran Blood Transfus Organ 2020, 17(4): 315-321 Back to browse issues page
A case report of temporary and acquired vitamin K-dependent clotting factor deficiency without any response to administrated vitamin K
Vahid Niazi , Massoumeh Shahbazi
Abstract:   (544 Views)
Abstract
Background and Objectives
Vitamin K-dependent clotting factor deficiency (VKCFD) is usually an acquired problem due to liver disease, malabsorption, and overdose of warfarin.  In the present paper the significance and role of vitamin K-dependent coagulation factors in menorrhagia were evaluated.
 
Case
We present a rare case of 43 year woman with acquired vitamin K deficiency and severe menorrhagia without any gynecological problem. The level of all Vitamin-K dependent coagulation factors, Fctor II, Factor VII, Factor IX, and Factor X decreased. Furthermore, even after multiple administration of Vitamin K  and its oral consumption, still the level of coagulation factors and menorrhagia did not ameliorate.
 
Conclusions 
Acquired VKCFD is one of the rare situations that can be life-threatening.
 
Keywords: Key words: Vitamin K, Menorrhagia, Clotting Factor
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Type of Study: case report | Subject: Hematology
Published: 2020/12/30


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Volume 17, Issue 4 (Winter 2020) Back to browse issues page