:: Volume 17, Issue 4 (Winter 2020) ::
Sci J Iran Blood Transfus Organ 2020, 17(4): 315-321 Back to browse issues page
A case report of temporary and acquired vitamin K-dependent clotting factor deficiency without any response to administrated vitamin K
Vahid Niazi , Massoumeh Shahbazi
Abstract:   (544 Views)
Background and Objectives
Vitamin K-dependent clotting factor deficiency (VKCFD) is usually an acquired problem due to liver disease, malabsorption, and overdose of warfarin.  In the present paper the significance and role of vitamin K-dependent coagulation factors in menorrhagia were evaluated.
We present a rare case of 43 year woman with acquired vitamin K deficiency and severe menorrhagia without any gynecological problem. The level of all Vitamin-K dependent coagulation factors, Fctor II, Factor VII, Factor IX, and Factor X decreased. Furthermore, even after multiple administration of Vitamin K  and its oral consumption, still the level of coagulation factors and menorrhagia did not ameliorate.
Acquired VKCFD is one of the rare situations that can be life-threatening.
Keywords: Key words: Vitamin K, Menorrhagia, Clotting Factor
Full-Text [PDF 386 kb]   (142 Downloads) |   |   Full-Text (HTML)  (290 Views)  
Type of Study: case report | Subject: Hematology
Published: 2020/12/30

XML   Persian Abstract   Print

Volume 17, Issue 4 (Winter 2020) Back to browse issues page