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:: Volume 17, Issue 2 (Summer 2020) ::
Sci J Iran Blood Transfus Organ 2020, 17(2): 133-139 Back to browse issues page
Blood Products Consumption Among Patients with Crimean-Congo Hemorrhagic Fever in Sistan and Baluchestan Province
S. Khosravi , M. Metanat , N. Pourkhosravi , Kh. Kazemi
Keywords: Hemorrhage, Blood Platelets, Fever
Full-Text [PDF 302 kb]   (649 Downloads)     |   Abstract (HTML)  (1896 Views)
Type of Study: Research | Subject: Infectious disease
Published: 2020/06/30
Full-Text:   (1400 Views)
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Sci J Iran Blood Transfus Organ 2020; 18 (2): 133-139
Original Article
 
Blood Products Consumption Among Patients with
Crimean-Congo Hemorrhagic Fever in Sistan and
Baluchestan Province
 
Khosravi S.1,2, Metanat M.2, Pourkhosravi N.3, Kazemi Kh.1,2
 
 
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Zahedan Blood Transfusion Center, Zahedan, Iran
3Infectious Diseases and Tropical Medicine Research Center , Zahedan University of Medical Sciences,  Zahedan, Iran
 
 
Abstract
Background and Objectives
The Crimean-Congo Hemorrhagic Fever (CCHF) is a hemorrhagic viral infection with a high mortality rate. Due to the lack of specific treatment, the disease is managed by medical supports and antiviral drugs. In the present study, we assessed the consumption of blood products during the last outbreak of CCHF in 2017 in Sistan and Baluchestan Province.
 
Materials and Methods
In this cross-sectional study, during the CCHF outbreak in 2016, all hospitalized patients with CCHF in the province, their disease status and used blood products were recorded. In addition, the probable causes of CCHF infection and response to treatment were recorded. The disease was diagnosed and confirmed in the patients by serological studies and reverse transcriptase polymerase chain reaction (RT-PCR). The statistical analysis was done by SPSS 16 and descriptive levels.
 
Results
During the study period, 18 patients with a definitive diagnosis of  Crimean-Congo Fever and mean age of 27.5 6 + 6.9 were hospitalized. All patients were male and most were slaughterhouse workers (44.5%). The main cause of CCHF contamination was contact with contaminated meat and infected livestock. Of the 18 patients, 11 (61%) required blood transfusions, and platelet concentrate was the most commonly used (83.2%) blood product among the patients. A total of 191 blood products units were consumed and none of the patients died from CCHF.
 
Conclusions 
CCHF is a hemorrhagic disease that required high rate of blood products transfusion, mostly platelet.
 
Key words: Hemorrhage, Blood Platelets, Fever
 
 
Received:    2 Sep 2019
Accepted: 16 Feb 2020
 
 

Correspondence: Khosravi S., MPH. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine and Zahedan Blood Transfusion Center.
Postal Code: 9813653415, Zahedan, Iran. Tel: (+9854) 33239500; Fax: (+9854) 33239500
E-mail: khosravi_sh@yahoo.com
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Khosravi S, Metanat M, Pourkhosravi N, Kazemi K. Blood Products Consumption Among Patients with Crimean-Congo Hemorrhagic Fever in Sistan and Baluchestan Province. Sci J Iran Blood Transfus Organ 2020; 17 (2) :133-139
URL: http://bloodjournal.ir/article-1-1305-en.html


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Volume 17, Issue 2 (Summer 2020) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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