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Sci J Iran Blood Transfus Organ 2020; 18 (2): 133-139
Original Article
Blood Products Consumption Among Patients with Crimean-Congo Hemorrhagic Fever in Sistan and Baluchestan Province Khosravi S.1,2, Metanat M.2, Pourkhosravi N.3, Kazemi Kh.1,2 1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran 2Zahedan Blood Transfusion Center, Zahedan, Iran 3Infectious Diseases and Tropical Medicine Research Center , Zahedan University of Medical Sciences, Zahedan, Iran Abstract Background and Objectives
The Crimean-Congo Hemorrhagic Fever (CCHF) is a hemorrhagic viral infection with a high mortality rate. Due to the lack of specific treatment, the disease is managed by medical supports and antiviral drugs. In the present study, we assessed the consumption of blood products during the last outbreak of CCHF in 2017 in Sistan and Baluchestan Province.
Materials and Methods
In this cross-sectional study, during the CCHF outbreak in 2016, all hospitalized patients with CCHF in the province, their disease status and used blood products were recorded. In addition, the probable causes of CCHF infection and response to treatment were recorded. The disease was diagnosed and confirmed in the patients by serological studies and reverse transcriptase polymerase chain reaction (RT-PCR). The statistical analysis was done by SPSS 16 and descriptive levels.
Results
During the study period, 18 patients with a definitive diagnosis of Crimean-Congo Fever and mean age of 27.5 6 + 6.9 were hospitalized. All patients were male and most were slaughterhouse workers (44.5%). The main cause of CCHF contamination was contact with contaminated meat and infected livestock. Of the 18 patients, 11 (61%) required blood transfusions, and platelet concentrate was the most commonly used (83.2%) blood product among the patients. A total of 191 blood products units were consumed and none of the patients died from CCHF.
Conclusions
CCHF is a hemorrhagic disease that required high rate of blood products transfusion, mostly platelet.
Key words: Hemorrhage, Blood Platelets, Fever
Received: 2 Sep 2019 Accepted: 16 Feb 2020
Correspondence: Khosravi S., MPH. Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine and Zahedan Blood Transfusion Center.
Postal Code: 9813653415, Zahedan, Iran. Tel: (+9854) 33239500; Fax: (+9854) 33239500
E-mail: khosravi_sh@yahoo.com
Khosravi S, Metanat M, Pourkhosravi N, Kazemi K. Blood Products Consumption Among Patients with Crimean-Congo Hemorrhagic Fever in Sistan and Baluchestan Province. Sci J Iran Blood Transfus Organ 2020; 17 (2) :133-139 URL: http://bloodjournal.ir/article-1-1305-en.html