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:: Volume 3, Issue 3 (Autumn 2006) ::
Sci J Iran Blood Transfus Organ 2006, 3(3): 243-251 Back to browse issues page
The efficacy of horse collagen(Antema) in hemostasis of bleeding due to dental procedures, pilonidal sinus surgery, hemorrhoidectomy and laminectomy
Mohebbi H.A , Abolghasemi H , Towliat Kashani S.M , Fanaii S.A , Kabir A
Abstract:   (19064 Views)

  Abstract

 Background and Objectives

 Hemostasis and control of bleeding are important principles in surgery. Control of bleeding with normal procedures such as cauterization and ligation is sometimes hard and even impossible. Considering different effects of collagen including hemostasis acceleration, complete absorption, tissue repair, and flexibility and appropriate traction, it can help maintain hemostasis.

 

 Materials and Methods

 In a randomized controlled clinical trial, 92 cases and 91 controls were compared. Horse collagen (Antema) was used in cases while routine procedures were implemented in controls. Patients were evaluated in 4 groups involving dental procedures, pilonidal sinus open surgery, hemorrhoidectomy, and laminectomy. Statistical indices such as mean, standard error, and statistical tests such as t-test and chi-square were used in the analysis.

 

 Results

 Mean age was 29.48 ± 1.29 in the cases and 33.2 + 1.5 in the control group. Seventy four (36 cases, 38 controls) undergoing dental procedures, 61(31 cases, 30 controls) pilonidal sinus open surgeries, 31(18 cases, 18 controls) hemorrhoidectomies, and 12(7 cases, 5 control) laminectomies were investigated. Despite higher severity of bleeding in cases (p=0.011, r=0.247), the time of bleeding control (p<0.001) and the time of complete hemostasis(p<0.001) were lower in cases than in the control group.

 

 Conclusions

 Antema is effective in hemostasis and it may be used as an adjunct material in hemostasis.

  

 Key words : Collagen, Hemorrhage, Hemostasis, Surgery 

Keywords: Array, Collagen, Hemorrhage, Hemostasis, Surgery
Full-Text [PDF 196 kb]   (2779 Downloads)    
Type of Study: Research | Subject: General
Published: 2014/08/18
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Mohebbi H.A, Abolghasemi H, Towliat Kashani S.M, Fanaii S.A, Kabir A. The efficacy of horse collagen(Antema) in hemostasis of bleeding due to dental procedures, pilonidal sinus surgery, hemorrhoidectomy and laminectomy. Sci J Iran Blood Transfus Organ 2006; 3 (3) :243-251
URL: http://bloodjournal.ir/article-1-104-en.html


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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 3, Issue 3 (Autumn 2006) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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