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Sci J Iran Blood Transfus Organ 2016; 13(1): 54-60
Original Article
The adverse reactions of autologus transfusion by ANH in cardiac surgery patients at Tehran Blood Center
Chegini A.1, Khorshidfar M.1, Rasouli M.1
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
Abstract Background and Objectives
One method of autologous transfusion is acute normovolemic hemodilution (ANH) that involves withdrawal of whole blood shortly before surgery with infusion of fluids to maintain normovolemia.
Materials and Methods
A retrospective study was carried out during 2013-2014 at Tehran Blood Centre. The data regarded different cardiac surgery hospitals which performed acute normovolemic hemodilution in their operating room. We analyzed adverse events included arrhythmia (atrial fibrillation, premature ventricular contraction) and unstable hemodynamic from collecting blood to 30 minutes.
Results
308 patients scheduled for acute normovolemic hemodilution during cardiac surgery and were evaluated adverse events. We assessed 266 (86.4%) Cardiopulmonary bypass graft patient, 20 (6.6%) patients mitral valve replacement and aorta valve replacement, two valves replacement concurrent in 3 (0.9%) patients (MVR + AVR) (MVR + TVR), 10 mitral valve replacement with CABG and, congenital heart disease in 7 (2.3%) patients and 2 (0.6%) Bental repair. No significant hemodynamic changes and arrhythmia were recorded.
Conclusions
In this survey, No patients didn't show any adverse events (arrhythmia and unstable hemodynamic) during and 30 minutes after phlebotomy. Acute normovolemic hemodilution safely could perform in cardiac surgery patients with CABG, valvular replacement.
Key words: Autologous Blood Transfusion, Blood Transfusion, Cardiac Surgery
Received: 19 Dec 2015 Accepted: 19 Jan 2016
Correspondence: Chegini A., MD. Specialist in Anesthesiology. Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 82052256; Fax: (+9821) 88601599
E-mail: a.chegini@ibto.ir
Chegini A, Khorshidfar M, Rasouli M. The adverse reactions of autologus transfusion by ANH in cardiac surgery patients at Tehran Blood Center. Sci J Iran Blood Transfus Organ 2016; 13 (1) :54-60 URL: http://bloodjournal.ir/article-1-1006-en.html