TY - JOUR T1 - Prevalence of clinical and paraclinical features of leukemia among children with acute lymphoblastic leukemia in Sanandaj Besat Hospital, 2008- 2013 TT - فراوانی علائم بالینی و آزمایشگاهی کودکان مبتلا به لوسمی لنفوبلاستیک حاد مراجعه‌کننده به بیمارستان بعثت سنندج از سال 1385 تا 1391 JF - Blood-Journal JO - Blood-Journal VL - 14 IS - 4 UR - http://bloodjournal.ir/article-1-1110-en.html Y1 - 2017 SP - 281 EP - 288 KW - Key words: Leukemia KW - Hemoglobin KW - ALL (Acute lymphoblastic leukemia N2 - Abstract Background and Objectives One of the most common childhood malignancies is leukemia with prevalance of 40 per million among children aged under 15. This study aimed to determine the prevalence of clinical and paraclinical features of leukemia among children aged under 15 with acute lymphoblastic leukemia. Materials and Methods In this cross-sectional analysis of hospital records, clinical and paraclinical features of patients admitted to Besat Hospital during 2006-2012 were reviewed. Data were analyzed by Stata (version 11) software. c2 test and t-test were used. Results Of the total study population (84 cases), 65.5% were male and 34.5% were female. The mean age was 6.13 ± 4/48 years. The most common clinical feauture was lethargy (78.6%) followed by history of fever (73.8%), pallor (34.5%), lymphadenopathy (29.8%), anemia (60.7%) and hepatosplenomegaly (48.8%). There was a significant correlation between T cell leukemia and lower hemoglobin level, and likewise with lower platelet count in children more than 8 years of age (p < 0.05). Conclusions This study revealed lethargy as the most common clinical feature in our study population. As well it showed a significant correlation between lower platelet count and age (above 8 years old); the same true between lower hemoglobin level and T cell leukemia. M3 ER -