[Home ] [Archive]   [ فارسی ]  
:: Main :: About us :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Subscription::
News& Events::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Indexing
                        
..
:: Volume 15, Issue 1 (Spring 2018) ::
Sci J Iran Blood Transfus Organ 2018, 15(1): 55-58 Back to browse issues page
Identification of an Iranian family with Rh null phenotype
E. Sabzikar , A. Baghernejad neshel , F. Hasani , A.A. Kiani , S. Alijani , M. Nezami , M. Emamifard
Keywords: Key words: Blood Transfusion, Phenotype, Antigen, Iran
Full-Text [PDF 235 kb]   (1485 Downloads)     |   Abstract (HTML)  (5308 Views)
Type of Study: case report | Subject: Imunohematology
Published: 2018/03/11
Full-Text:   (10708 Views)
    References:
  1. Gol Afsahan H, Sharifzadeh S, Ghahremani M. Principle and laboratory procedure on blood banks. 2nd ed. Shiraz: Publication of Shiraz University of Medical Science; 2014. p. 79-95. [Persian]
  2. Hilleyer ChD, Silberstein LE, Ness PM. Blood banking and transfusion Medicine. 2nd ed. USA: Churchill  Livingstone Elsevier; 2007. p. 81-6.
  3. Abdi J, Kiani AA. Seroepidemiologic evaluation of Rh system major antigens (D,C,E,c,e) and their phenotypes among the blood donors in Khorramabad, Iran. Sci J Iran Blood Transfus Org 2009; 6(3): 219-26. [Article in Farsi]
  4. Avent ND, Reid ME. The Rh blood group system: a review. Blood 2000; 95(2): 375-87.
  5. Harmening DM. Modern Blood Banking and Transfusion Practice. 5th ed. Philadelphia: F.A. Davis Company; 2005. p. 143-4.
  6. Ballas   SK,   Clark    MR,    Mohandas  N, Colfer HF,
 
 
Caswell MS, Bergren MO, et al. Red cell membrane and cation deficiency in Rh null syndrome. Blood 1984; 63(5): 1046-55.
  1. Qureshi A, Salman M, Moiz B. Rhnull: a rare blood group phenotype. J Pak Med Assoc 2010; 60(11): 960-1.
  2. Shaiegan M, Samiee Sh, Azarkeivan A, Daneils J, Martin P, Ataiee Z, et al. Molecular blood genotyping in patients with Thalassemiamajor in Tehran Adult Thalassemic Clinic. Sci J Iran Blood Transfus Organ 2009; 6(2): 107-15. [Article in Farsi]
  3. McPherson RA, Pincus MR. Henry’s clinical diagnosis and management by laboratory methods. 22nd ed. Philadelphia: Saunders Elsevier; 2011. p. 700-1.
  4. Cartron JP. Defining the Rh blood group antigens. Biochemistry and molecular genetics. Blood Rev 1994; 8(4): 199-212.
 
 
 


 
 
 
 
Sci J Iran Blood Transfus Organ 2018; 15(1): 55-58
Case Report
 

 

Identification of an Iranian family with Rh null phenotype
 
Sabzikar E.1,2, Baghernejad Nashl A.1,2, Hasani F.1, Kiani A.A.1,2, Alijani S.1,2, Nezami M.1,2
Emami Fard M.1,2
 
 
 
 
1Blood  Transfusion  Research  Center,  High  Institute  for  Research  and  Education  in  Transfusion Medicine, Tehran, Iran
2Qazvin Regional Blood Transfusion Center, Qazvin, Iran
 
 
 
 
Abstract
Background and Objectives
Rh blood group system is one of the complex systems of blood groups and composed of nearly 50 antigens. The two gens of Rh D and Rh CE are responsible for coding of Rh system. Rh null genotype does not express any of these antigens. The prevalence of phenotype Rh null is 1 person per every 6×106 individuals and it is rather difficult to find compatible blood for the recipients in need. However, as there are probably members with similar characteristics in a given family, it would be plausible to diagnose the phenotype in family members to prepare compatible blood in time of need.
 
Case
In 2014, a 39-year-old negative female patient with hemolytic anemia referred to BoAli Hospital in Qazvin. Her sample, due to incompatibility in cross matching was further tested and her Rh null group was determined.
 
Conclusions 
This case was identified by antibody screening tests and the subsequent determination of Rh antigen phenotype. After checking other family members, her brother was identified as the second Rh null group case in the country.
 
Key words: Blood Transfusion, Phenotype, Antigen, Iran
 
 
 
 
 
 
 
 
 
 
Received: 17 Aug 2015
Accepted:  3 Feb 2018
 
 

Correspondence: Sabzikar E., MSc of Hematology & Blood Banking. Blood  Transfusion  Research  Center,  High  Institute  for  Research  and  Education  in  Transfusion Medicine and Qazvin Regional Blood Transfusion Center.
Postal Code: 3416613445, Qazvin, Iran. Tel: (+9828) 12246727; Fax: (+9828) 12220136
E-mail:
sabzikar.seven1986@yahoo.com
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sabzikar E, Baghernejad neshel A, Hasani F, Kiani A, Alijani S, Nezami M et al . Identification of an Iranian family with Rh null phenotype . Sci J Iran Blood Transfus Organ 2018; 15 (1) :55-58
URL: http://bloodjournal.ir/article-1-982-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 15, Issue 1 (Spring 2018) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
Persian site map - English site map - Created in 0.05 seconds with 39 queries by YEKTAWEB 4645