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:: Volume 2, Issue 6 (Winter 2006) ::
Sci J Iran Blood Transfus Organ 2006, 2(6): 273-276 Back to browse issues page
A report of a Bombay phenotype case (oh) in Challus Blood Transfusion center
Kiadaliri K. , Jahed B. , Mashayekh A. , Pasha Zanosi M.
Abstract:   (28609 Views)

  Abstract

  

 Background and Objectives

  Bombay phenotype donors do not have H Antigen on the surface of their red blood cells and have hemolytic anti-H in their sera so, this group should receive autologous blood and donation of their blood as O blood group can lead to severe hemolysis in recipients. Therefore, it is important to detect them.

 

  Case

  A 46-year-old man living in Bushehr for many years has been recognized as O+ blood group. Preliminary diagnosis was made by the use of antibody screening agglutination test. In serologic studies, we detected high level of anti-H, anti-A, and anti-B. Direct coombs was also negative. Definite diagnosis was made with no red cell agglutination in the presence of anti-H. Complementary serologic studies showed that Kelly antigen was negative and Rh genotype was CD/cde.

 

 Conclusions

  This case increased the number of Bombay phenotypes in the world to 131 and in Iran to 11. It seems that this latter number is higher than official estimations of its prevalence (10-6). Therefore, the use of antibody screening test should be considered in screening blood donations.

  

  

 Key words: Bombay, phenotype, Blood donors, H blood group system, anti-H, Autologous transfusion

Keywords: Bombay, phenotype, Blood donors, H blood group system, anti-H, Autologous transfusion
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Type of Study: Research | Subject: General
Published: 2014/08/19
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Kiadaliri K., Jahed B., Mashayekh A., Pasha Zanosi M.. A report of a Bombay phenotype case (oh) in Challus Blood Transfusion center. Sci J Iran Blood Transfus Organ 2006; 2 (6) :273-276
URL: http://bloodjournal.ir/article-1-97-en.html


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Volume 2, Issue 6 (Winter 2006) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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