Abstract

Background and Objectives

Unexpected alloantibodies in the sera of patients who have a history of blood transfusion or pregnancy were found; they caused complications in a patient following blood transfusion.

Case

A 30-year-old woman with a history of five abortions at months 7 and 9 and with a history of 4 units of blood transfusion in one of her pregnancies referred for screening tests at the week 19th of her pregnancy. In antibody screening and genotyping, 2 cells of the 3 cells of the triple panel and 8 cells of the 11 cells of the triple panel showed positive reactions at different temperature degrees, respectively. Selected Cells and Enzyme treatment were used for the final confirmation of antibody typing.

Conclusions 

The studies show that the incidence of these alloantibodies is higher in the sera of patients who have a history of blood transfusion and recurrent pregnancies. Based on the results, it is recommended for the patients with anti-D and –E to receive blood components free of these two antigens.

Key words: Alloantibodies, Previous Abortion, screening