[Home ] [Archive]   [ فارسی ]  
:: Main :: About us :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Subscription::
News& Events::
Contact us::
Site Facilities::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
Indexing
                        
..
:: Volume 10, Issue 2 (Summer 2013) ::
Sci J Iran Blood Transfus Organ 2013, 10(2): 140-146 Back to browse issues page
Assessment of plateletphersis donation in Tehran Blood Center
A. Chegini , S.M. Mirrezaie , M. Poorreza , A.R. Rezaie , A.J. Anbardan
Keywords: Key words : Plateletpheresis, side effects, Blood Donation
Full-Text [PDF 222 kb]   (6268 Downloads)     |   Abstract (HTML)  (39095 Views)
Type of Study: Research | Subject: Blood transfusion medicine
Published: 2013/08/24
Full-Text:   (78485 Views)
References:
  1. Hillyer CD, Silberstein LE, Ness PM, Anderson KC, Roback JD. Blood Banking and Transfusion Medicine: Basic Principles and Practice. 2nd ed. Edinburg: Churchill Livingstone; 2006. p. 172-4, 183-4.
  2. Mcleod BC. Apheresis: Principles and Practice. 2nd ed. Germany: S Karger Pub; 2003. p. 23-8.
  3. Franchini M, Gandini G, Gandini AR, Crocco I, de Gironcoli M, Bertuzzo D, et al. Frequency of Adverse Events during Blood and Apheresis Donations: A Single-Center Study. Infus Ther Transfus Med 2002; 29(4): 200-5.
  4. Garozzo G, Crocco I, Giussani B, Martinucci A, Monacelli S, Randi V. Adverse reactions to blood donations: the READ project. Blood Transfus 2010; 8(1): 49-62.
  5. Crocco I, Franchini M, Garozzo G, Gandini AR, Gandini G, Bonomo P, et al. Adverse reactions in blood and apheresis donors: experience from two Italian transfusion centres. Blood Transfus 2009; 7(1): 35-8.
  6. Roback J, Rae Combs M, Grossman B, Hillyer C. Technical Manual. 16th ed. Edinburg: AABB; 2008. p. 152-3, 163, 167, 169, 195-7, 231.
  7. Maurício R, de Sousa G, Seghatchian J. What's happening: an overview of potential adverse reactions associated with apheresis technology. Transfus Apher Sci 2005; 33(3): 351-6.
  8. McLeod BC, Price TH, Owen H, Ciavarella D, Sniecinski I, Randels MJ, et al. Frequency of immediate adverse effects associated with apheresis donation. Transfusion 1998; 38(10): 938-43.
  9. Rogers RL, Johnson H, Ludwig G, Winegarden D, Randels MJ, Strauss RG. Efficacy and safety of plateletpheresis by donors with low-normal platelet counts. J Clin Apher 1995; 10(4): 194-7.
  10. Bongiovanni MB, Katz RS, Wurzel HA. Long-term plateletpheresis of a donor. Transfusion 1980; 20(4): 465-6.
 
  1. Huestis DW. Risks and safety practices in hemapheresis procedures. Arch Pathol Lab Med 1989; 113(3): 273-8.
  2. Mcleod BC. Apheresis: Principles and Practice. 3rd ed. Germany: S Karger Pub; 2010. p. 47, 54-5, 57, 118, 284-5.
  3. Sorensen BS, Johnsen SP, Jorgensen J. Complications related to blood donation: a population-based study. Vox Sang 2008 ; 94(2): 132-7.
  4. France CR, France JL, Roussos M, Ditto B. Mild reactions to blood donation predict a decreased likelihood of donor return. Transfus Apher Sci 2004; 30(1): 17-22.
  5. Kasprisin DO, Glynn SH, Taylor F, Miller KA. Moderate and severe reactions in blood donors. Transfusion 1992; 32(1): 23-6.
  6. Komatsu F, Shikata M. Abnormal electrocardiographic findings in apheresis donors. Transfusion 1988; 28(4): 371-4.
  7. Grindon AJ. Adverse reactions to whole blood donation and plasmapheresis. Crit Rev Clin Lab Sci 1982; 17(1): 51-75.
  8. De Silvestro G, Marson P, Russo GE, Vicarioto M, Donadel C. National survey of apheresis activity in Italy (2000). Transfus Apher Sci 2004; 30(1): 61-71.
  9. Bolan CD, Wesley RA, Yau YY, Cecco SA, Starling J, Oblitas JM, et al. Randomized placebo-controlled study of oral calcium carbonate administration in plateletpheresis: I. Associations with donor symptoms. Transfusion 2003; 43(10): 1403-13.
  10. Despotis GJ, Goodnough LT, Dynis M, Baorto D, Spitznagel E. Adverse events in platelet apheresis donors: A multivariate analysis in a hospital-based program. Vox Sang 1999; 77(1): 24-32.
  11. Makar YF, Butler MO, Cockersole GM, Gabra G, Serevitch JM. National audit of citrate toxicity in plateletpheresis donors. Transfus Med 2002; 12(3): 187-91.



 
Original Article
 
 
 
 
Sci J Iran Blood Transfus Organ 2013; 10(2): 140-146
 
 
 

Assessment of plateletphersis donation in Tehran
Blood Center
 
Chegini A.1,2, Mirrezaie M.1,2, Poorreza M.1,2, Rezaie A.R.1,2,  Anbardan A.J.1,2
 
 
 
1Blood Transfusion Research Center, High Institute for Research and Education on Transfusion Medicine, Tehran, Iran
2Tehran Regional Educational Blood Transfusion Center, Tehran, Iran
 
 
 
Abstract
Background and Objectives
Additional and more effective platelets can be gained through plateletphersis which at times equals platelets of 8 units of blood. Patients are exposed to a less number of donors through prescription of such platelets. Although side-effects of plateletphersis are low among donors but side-effects vary at different centers.  Illustration of plateletphersis production side-effects at Tehran Blood Bank is the aim.
 
Materials and Methods
This is a retrospective study on plateletphersis donors from 2005 to March 2011. Research was carried on 309 total blood donors who met Iran blood transfusion standards; CBC was carried out on all donors and those with Hb and platelet higher than 12.5 and 150.000 were entered into the study.  Information regarding aphersis sessions was compiled in donors’ forms including side-effects during platelet donation and they were classified as mild, intermediate  and severe according to definition.
 
Results
In the study, 302 cases of plateletphersis were carried out in which 81% of donors were male and 19% female; while the mean age of donors was 35.3 ± 9.8 .  The most occurring side-effects among donors were mild/medium vasovagal donation reaction 1.6% and citrate poisoning 1.6% of which 0.3% was of the intermediate type.
 
Conclusions 
Plateletphersis is safe and occurrence of side-effects is low.  Side-effects occur mostly among younger and first time donors.
 
Key words: Plateletpheresis, side effects, Blood Donation
 
 
 
 
 
Received: 7 Dec 2010
Accepted:9 Feb 2013
 

Correspondence: Chegini A., MD. Specialist in Anesthesiology. Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education on Transfusion Medicine and Tehran Regional Educational Blood
             Transfusion Center.
             P.O.Box: 14166-13141, Tehran, Iran. Tel: (+9821) 88963034; Fax: (+9821) 88959096
             E-mail: azita_chegini@yahoo.com
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Chegini A, Mirrezaie S, Poorreza M, Rezaie A, Anbardan A. Assessment of plateletphersis donation in Tehran Blood Center . Sci J Iran Blood Transfus Organ 2013; 10 (2) :140-146
URL: http://bloodjournal.ir/article-1-767-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 10, Issue 2 (Summer 2013) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
Persian site map - English site map - Created in 0.07 seconds with 39 queries by YEKTAWEB 4645