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:: Volume 8, Issue 2 (Summer 2011) ::
Sci J Iran Blood Transfus Organ 2011, 8(2): 137-142 Back to browse issues page
Prevalence of HCV among thalassemia patients in Shahid Bahonar Hospital, Karaj
M. Kashanchi Langarodi Dr. * , H. Abdolrahim Poorheravi Dr.
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Prevalence of HCV among thalassemia patients in Shahid Bahonar Hospital, Karaj Kashanchi Langarodi M.1, Abdolrahim Poorheravi H.2 1Alborz University of Medical Science and Health Services, Karaj, Iran 2General Physician Abstract Background and Objectives Although recent screening policies have markedly decreased the incidence of HCV infection in transfusion dependent thalassemia paitients, this problem is still one of the most important causes of mortality and morbidity in thalassemic patients. Materials and Methods A retrospective cross-sectional study was conducted on 206 thalassemia patients referred to the Shahid Bahonar Hospital during 2009-2010 .Serum specimens were tested with anti –HCV assay and RIBA –II technique to asses HCV infection. Statistical analysis was done with SPSS18 (χ2 and T-test). Results The overall prevalence rate of anti-HCV was 15% )11 male, 20 female). Moreover 29 anti-HCV positive patients were RIBA –II positive(11 male, 18 female). All HCV affected patients but one had received their first transfusion before 1996 when HCV screening had became mandatory. Conclusions HCV infection rate compared with the general population is higher in multi transfused thalassemia patients. Out of HCV infected thalassemias, 80% are at risk of developing chronic liver diseases and fibrosis thus preventive measures such as blood donor screening for anti-HCV and stringent infection control procedures are crucial steps to be implemented for HCV prevention. Key words: Hepatitis C, Thalassemia, Hepatitis C Antibodies Sci J Iran Blood Transfus Org 2011 8(2): 137-142 Received: 26 Oct 2010 Accepted: 7 Feb 2011 Correspondence: Kashanchi Langarodi M., MD. Pediatrician, Alborz University of Medical Science and Health Services, Shahid Bahonar Hospital, Chaloos street. Postal Code: 3154686695, Karaj, Iran. Tel: (+98261)2500123 Fax: (+98261)2509255 E-mail: Mojgan.kashanchi@yahoo.com
Keywords: Hepatitis C, Thalassemia, Hepatitis C Antibodies
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Type of Study: Research | Subject: Infectious disease
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Kashanchi Langarodi M, Abdolrahim Poorheravi H. Prevalence of HCV among thalassemia patients in Shahid Bahonar Hospital, Karaj. Sci J Iran Blood Transfus Organ. 2011; 8 (2) :137-142
URL: http://bloodjournal.ir/article-1-488-en.html


Volume 8, Issue 2 (Summer 2011) Back to browse issues page
فصلنامه پژوهشی خون Scientific Journal of Iran Blood Transfus Organ
The Scientific Journal of Iranian Blood Transfusion Organization - Copyright 2006 by IBTO
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