Abstract

 Background and Objectives

  Cytomegalovirus (CMV) causes infection in immunocompromised, transplant recipients and those who receive blood transfusion frequently. Latent and dormant CMV infection can be reactivated in immunocompromised patients and cause fulminant infection. Risk factors for primary CMV infection are blood transfusion (including clotting factors, etc.), recipients of infected transplants, hemodialysis, and the frequency of dialysis in a week. In order to evaluate the serologic status of hemodialysis patients in Labbafinejad Hospital, we have done this descriptive study.

  Materials and Methods 

  A descriptive study (cross-sectional) was designed in 54 hemodialysis patients in Labbafinejad Hospital. With ELISA technipue and with RADIM kit, IgM and IgG titers were determined. Titers greater than 1.1 ISR were considered positive and less than 0.9 ISR negative. Titers between 0.9 ISR and 1.1 ISR were considered equivocal and deleted. After primary data collection procedure aiming at evaluating relationships between parameters, Chi-square test and Fisher's exact test were used.

 Results

 In our study 54 patients who regularly underwent hemodialysis were studied. Twenty-nine patients were male and 25 female with the age range of 53 ± 16. Mean dialysis length was 81.7± 69.4. In the time of evaluation, 49 patients (91%) were anti-CMV IgG positive and 10 were anti-CMV IgM positive. There was no relationship between the antibody titer and dialysis duration. There was found to be an indirect significant correlation between the CMV IgG titer and dialysis frequency (r=-0.31, P<0.024).

 Conclusions

 Therefore, we recommend that every patient who was undergone hemodialysis receive blood products free of CMV.