|
Evaluation of the quality of platelet components in Azarbaijan Sharghi Province: the comparison in the PSL between a blood
center and a hospital
|
R. Yaghoubi   , K. Shamsasanjan , Gh. Karimi , M. Zadsar |
|
|
| Keywords: Key words: Platelet Transfusion, Quality Control, Blood Platelets, Platelet Count |
|
|
Full-Text [PDF 432 kb]
(1123 Downloads)
| Abstract (HTML) (4905 Views)
|
Type of Study: Research |
Subject:
Blood Transfusion
Published: 2017/12/30
|
|
|
|
|
|
|
Full-Text: (5239 Views) |
References:
- Coêlho MJ, Monteiro Tde C, Vasquez FG, Silva KL, Dos Santos KS, de Oliveira VM, et al. Platelet aggregation and quality control of platelet concentrates produced in the Amazon Blood Bank. Rev Bras Hematol Hemoter 2011; 33(2): 110-4.
- Goodrich RP, Li J, Pieters H, Crookes R, Roodt J, Heyns Adu P. Correlation of in vitro platelet quality measurements with in vivo platelet viability in human subjects. Vox Sang 2006; 90(4): 279-85.
- Murphy S, Gardner FH. Effect of storage temperature on maintenance of platelet viability--deleterious effect of refrigerated storage. N Engl J Med 1969; 280(20): 1094-8.
- Ali SF. Platelet Activation in Stored Platelet
Concentrates: Comparision of Two Methods Preparation. J Blood Disord Transfus 2011; 2(2): 107.
- Maurer-Spurej E, Chipperfield K. Past and future approaches to assess the quality of platelets for transfusion. Transfus Med Rev 2007; 21(4): 295-306.
- Dijkstra-Tiekstra MJ, Pietersz RN, Huijgens PC. Correlation between the extent of platelet activation in platelet concentrates and in vitro and in vivo parameters. Vox Sang 2004; 87(4): 257-63.
- Ab Rahman WS, Hock LS, Asma S, Hassan R. Quality Assessment of Platelet Concentrates by Platelet Rich Plasma: A single Institution Experience. Int Med J
2013; 20(6): 755-8 .
- Ypma PF, van der Meer PF, Heddle NM, van Hilten
JA, Stijnen T, Middelburg RA, et al. A study protocol for a randomised controlled trial evaluating clinical effects of platelet transfusion products: the Pathogen Reduction Evaluation and Predictive Analytical Rating Score (PREPAReS) trial. BMJ Open 2016; 6(1): e010156.
- Loza-Correa M, PerkinsH, Kumaran D, Kou Y, Qaisar R, Geelhood S, et al. Noninvasive pH monitoring for bacterial detection in platelet concentrates. Transfusion 2016; 56(6): 1348-55.
- Soleimany Ferizhendy A, Aghaiepour M, Pourfathollah AA. Evaluation of platelet activation in platelet concenterates during storage in the Quality Control Laboratory of Iranian Blood Transfusion Organization in 2004. Sci J Iran Blood Transfus Organ 2005; 2(5): 163-9. [Article in Farsi]
- Ghezelbash B, Amini Kafiabad S, Hojjati MT, Hamidpoor M, Vaeli S, Tabtabae MR, et al. In
Vitro Assessment of Platelet Lesions during 5-day Storage in Iranian Blood Transfusion Organization (IBTO) Centers. Arch Iran Med 2015; 18(2): 114-6.
- Fung MK, Grossman BJ, Hillyer ChD, Westhoff CM. Technical Manual. 18th ed; 2014. p. 150.
- Pourmokhtar M, Salek Moghaddam E, Abbasi F, Zarei N. Comparative Study of Four Platelet-Rich Plasma Methods for Preparing Platelet Concentrates. IJBC 2013; 6(3): 103-7.
- Deyhim MR, Mesbah-Namin SA, Yari F, Taghikhani M, Amirizadeh N. L-carnitine effectively improves the metabolism and quality of platelet concentrates during storage. Ann Hematol 2015; 94(4): 671-80.
- Hamda EL-Sayed AH, Rania Fawzy, Manal Zahran, Ola Mahmoud, Emad Yacoub, Azza Moustafa. Impact of Different Preparation Methods on the In Vitro Quality of 8 Days Storage Platelet Concentrates. Life Sci J 2014; 11(1): 50-7.
|
Sci J Iran Blood Transfus Organ 2018; 14(4): 261-271
|
Evaluation of the quality of platelet components in Azarbaijan Sharghi Province: the comparison in the PSL between a blood
center and a hospital
Yaghoubi R.1, Shamsasenjan K.2, Karimi Gh.1, Zadsar M.1
1Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran
2Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract
Background and Objectives
Platelet concentrates are the most vulnerable blood products with the shortest shelf life. The aim was to assess the quality of produced platelet concentrates in the East Azerbaijan. In addition, the quality of products stored in the blood center was compared by products stored in one hospital during the period of five days.
Materials and Methods
In this descriptive study, thirty random donor platelet concentrates during 3 months from April to August 2015 were enrolled in the study. They were randomly classified into two groups, half were sent to the hospital and half remained in the blood center. The changes of their quality (platelet count, WBC count, MPV, pH, bacterial contamination, and CD62P and CD63 expression levels) were examined in the first, third and fifth days of storage in each group and comparison was made by accomplishing the paired sample t-test and t-test as deemed appropriate.
Results
All PCs on the first day met the national standard criteria; however, the quality parameters decreased significantly during storage. In addition there were no significant differences in the storage related changes in the quality between the blood center and hospital.
Conclusions
The quality of PCs produced in the blood center decreased during the storage time. By improving the storage conditions in the blood centers, it might be possible to extend the storage time of PCs by an acceptable quality. The significant difference was not observed between the platelets stored in the blood center compared to that stored in the hospital.
Key words: Platelet Transfusion, Quality Control, Blood Platelets, Platelet Count
Received: 11 Dec 2016
Accepted: 21 Jun 2017
Correspondence: Zadsar M., MD. Specialist in Infectious Diseases and Tropical Medicine. Assistant Professor of Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine.
P.O.Box: 14665-1157, Tehran, Iran. Tel: (+9821) 88629615; Fax: (+9821) 88628741
E-mail: maryam_zad@yahoo.com
|
|
| Send email to the article author |
|
|
|
| Add your comments about this article |
|
|
|
|
Yaghoubi R, Shamsasanjan K, Karimi G, Zadsar M. Evaluation of the quality of platelet components in Azarbaijan Sharghi Province: the comparison in the PSL between a blood
center and a hospital . Sci J Iran Blood Transfus Organ 2017; 14 (4) :261-271 URL: http://bloodjournal.ir/article-1-1096-en.html
|
.jpg)
.png)
